Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'TRAF2 and NCK-interacting protein kinase' and Ligand = 'BDBM585271'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM585271 (US11530197, Compound 99) Show SMILES CC(C)n1cnc(c1-c1nc(c[nH]1)C(=O)Nc1ccc(cc1)N1CCN(CC1)C(N)=O)-c1ccc(F)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The required volume of the 50× stock of test compound was added to the assay before a reaction mix containing the enzyme and substrate was added. The...				Citation and Details BindingDB Entry DOI: 10.7270/Q270858G
					More data for this Ligand-Target Pair
TRAF2 and NCK-interacting protein kinase (Homo sapiens (Human))	BDBM585271 (US11530197, Compound 99) Show SMILES CC(C)n1cnc(c1-c1nc(c[nH]1)C(=O)Nc1ccc(cc1)N1CCN(CC1)C(N)=O)-c1ccc(F)cc1 Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description TNIK(h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM RLGRDKYKTLRQIRQ, 10 mM Magnesium Acetate and [gamma-33P-ATP](specific activity a...				Citation and Details BindingDB Entry DOI: 10.7270/Q2GF0ZCZ
					More data for this Ligand-Target Pair