Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Leukotriene B4 receptor 1
(Homo sapiens (Human)) | BDBM50286748
((3R,4S)-3-Pyridin-2-ylmethyl-7-(1-quinolin-2-yl-et...)Show SMILES CC(Oc1ccc2[C@@H](O)[C@H](Cc3ccccn3)COc2c1)c1ccc2ccccc2n1 Show InChI InChI=1S/C26H24N2O3/c1-17(23-12-9-18-6-2-3-8-24(18)28-23)31-21-10-11-22-25(15-21)30-16-19(26(22)29)14-20-7-4-5-13-27-20/h2-13,15,17,19,26,29H,14,16H2,1H3/t17?,19-,26+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| 240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) |
Bioorg Med Chem Lett 5: 887-892 (1995)
Article DOI: 10.1016/0960-894X(95)00135-G BindingDB Entry DOI: 10.7270/Q2J966BX |
More data for this Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(GUINEA PIG) | BDBM50286748
((3R,4S)-3-Pyridin-2-ylmethyl-7-(1-quinolin-2-yl-et...)Show SMILES CC(Oc1ccc2[C@@H](O)[C@H](Cc3ccccn3)COc2c1)c1ccc2ccccc2n1 Show InChI InChI=1S/C26H24N2O3/c1-17(23-12-9-18-6-2-3-8-24(18)28-23)31-21-10-11-22-25(15-21)30-16-19(26(22)29)14-20-7-4-5-13-27-20/h2-13,15,17,19,26,29H,14,16H2,1H3/t17?,19-,26+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against leukotriene D4 receptor |
Bioorg Med Chem Lett 5: 887-892 (1995)
Article DOI: 10.1016/0960-894X(95)00135-G BindingDB Entry DOI: 10.7270/Q2J966BX |
More data for this Ligand-Target Pair | |
Leukotriene B4 receptor 1
(Homo sapiens (Human)) | BDBM50286748
((3R,4S)-3-Pyridin-2-ylmethyl-7-(1-quinolin-2-yl-et...)Show SMILES CC(Oc1ccc2[C@@H](O)[C@H](Cc3ccccn3)COc2c1)c1ccc2ccccc2n1 Show InChI InChI=1S/C26H24N2O3/c1-17(23-12-9-18-6-2-3-8-24(18)28-23)31-21-10-11-22-25(15-21)30-16-19(26(22)29)14-20-7-4-5-13-27-20/h2-13,15,17,19,26,29H,14,16H2,1H3/t17?,19-,26+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against human neutrophil leukotriene B4 (LTB4) induced Chemotaxis |
Bioorg Med Chem Lett 5: 887-892 (1995)
Article DOI: 10.1016/0960-894X(95)00135-G BindingDB Entry DOI: 10.7270/Q2J966BX |
More data for this Ligand-Target Pair | |