Found 16 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y2R expressed in CHO cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PP from human Y4R expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 790 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 794 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y5R expressed in HEK293 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [125I]-PYY(1 to 36 residues) from human Y1R expressed in BHK-21 cell membranes after 2 hrs by scintillation proximity assay |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y1R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y4R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 398 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y5R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | <1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y4R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y2R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y2R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y1R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50466563
(CHEMBL4294418)Show SMILES CC[C@H](C)[C@@H]1NC(=O)[C@H](CCC(=O)NCCCC[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CCCCCNC(=O)[C@H](CCCCN)NC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1 |r| Show InChI InChI=1S/C104H164N32O25/c1-8-57(6)84-99(158)127-67(19-11-13-41-105)87(146)117-43-14-9-10-24-82(144)122-68(21-16-44-118-102(109)110)88(147)131-76(51-62-53-115-54-121-62)96(155)130-75(49-60-27-33-64(139)34-28-60)95(154)129-74(47-55(2)3)94(153)132-77(52-80(108)142)97(156)125-69(20-12-15-42-116-81(143)40-38-73(93(152)135-84)123-86(145)66(106)48-59-25-31-63(138)32-26-59)92(151)134-83(56(4)5)98(157)136-85(58(7)137)100(159)128-71(23-18-46-120-104(113)114)89(148)126-72(37-39-79(107)141)91(150)124-70(22-17-45-119-103(111)112)90(149)133-78(101(160)161)50-61-29-35-65(140)36-30-61/h25-36,53-58,66-78,83-85,137-140H,8-24,37-52,105-106H2,1-7H3,(H2,107,141)(H2,108,142)(H,115,121)(H,116,143)(H,117,146)(H,122,144)(H,123,145)(H,124,150)(H,125,156)(H,126,148)(H,127,158)(H,128,159)(H,129,154)(H,130,155)(H,131,147)(H,132,153)(H,133,149)(H,134,151)(H,135,152)(H,136,157)(H,160,161)(H4,109,110,118)(H4,111,112,119)(H4,113,114,120)/t57-,58+,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,83-,84-,85-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 400 | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Activation of human Y5R expressed in HEK293 cells assessed as inhibition of isoproterenol-induced increase in intracellular cAMP levels by calcium 5 ... |
J Med Chem 61: 10519-10530 (2018)
Article DOI: 10.1021/acs.jmedchem.8b01046
BindingDB Entry DOI: 10.7270/Q2ZC85JC |
More data for this
Ligand-Target Pair | |