Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Angiotensin-converting enzyme
(Oryctolagus cuniculus) | BDBM50085457
(CHEMBL89533 | {(S)-6-[(R)-2-Benzyl-3-(formyl-hydro...)Show SMILES CC1(C)CCC[C@H](NC(=O)[C@@H](CN(O)C=O)Cc2ccccc2)C(=O)N1CC(O)=O Show InChI InChI=1S/C21H29N3O6/c1-21(2)10-6-9-17(20(29)24(21)13-18(26)27)22-19(28)16(12-23(30)14-25)11-15-7-4-3-5-8-15/h3-5,7-8,14,16-17,30H,6,9-13H2,1-2H3,(H,22,28)(H,26,27)/t16-,17+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Angiotensin I converting enzyme |
Bioorg Med Chem Lett 10: 257-60 (2000)
BindingDB Entry DOI: 10.7270/Q2BK1BJ8 |
More data for this Ligand-Target Pair | |
Neprilysin
(Rattus norvegicus (Rat)) | BDBM50085457
(CHEMBL89533 | {(S)-6-[(R)-2-Benzyl-3-(formyl-hydro...)Show SMILES CC1(C)CCC[C@H](NC(=O)[C@@H](CN(O)C=O)Cc2ccccc2)C(=O)N1CC(O)=O Show InChI InChI=1S/C21H29N3O6/c1-21(2)10-6-9-17(20(29)24(21)13-18(26)27)22-19(28)16(12-23(30)14-25)11-15-7-4-3-5-8-15/h3-5,7-8,14,16-17,30H,6,9-13H2,1-2H3,(H,22,28)(H,26,27)/t16-,17+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
| Assay Description Inhibition of Neutral endopeptidase |
Bioorg Med Chem Lett 10: 257-60 (2000)
BindingDB Entry DOI: 10.7270/Q2BK1BJ8 |
More data for this Ligand-Target Pair | |