Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50049079
(CHEMBL322349 | Propionic acid 3-(2-dimethylamino-e...)Show InChI InChI=1S/C15H20N2O2/c1-4-15(18)19-12-5-6-14-13(9-12)11(10-16-14)7-8-17(2)3/h5-6,9-10,16H,4,7-8H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description Binding affinity of the compound towards 5-hydroxytryptamine 1D receptor was determined in calf striatum homogenate |
J Med Chem 39: 314-22 (1996)
Article DOI: 10.1021/jm950498t BindingDB Entry DOI: 10.7270/Q2DJ5DRK |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50049079
(CHEMBL322349 | Propionic acid 3-(2-dimethylamino-e...)Show InChI InChI=1S/C15H20N2O2/c1-4-15(18)19-12-5-6-14-13(9-12)11(10-16-14)7-8-17(2)3/h5-6,9-10,16H,4,7-8H2,1-3H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 59 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description Binding affinity for recombinant human 5-hydroxytryptamine 1D receptor beta was determined using [3H]-5-HT as radioligand |
J Med Chem 39: 314-22 (1996)
Article DOI: 10.1021/jm950498t BindingDB Entry DOI: 10.7270/Q2DJ5DRK |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50049079
(CHEMBL322349 | Propionic acid 3-(2-dimethylamino-e...)Show InChI InChI=1S/C15H20N2O2/c1-4-15(18)19-12-5-6-14-13(9-12)11(10-16-14)7-8-17(2)3/h5-6,9-10,16H,4,7-8H2,1-3H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 405 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University
Curated by ChEMBL
| Assay Description In vitro affinity at human cloned 5-hydroxytryptamine 1A receptor by [3H]-8-OH-DPAT displacement. |
J Med Chem 39: 314-22 (1996)
Article DOI: 10.1021/jm950498t BindingDB Entry DOI: 10.7270/Q2DJ5DRK |
More data for this Ligand-Target Pair | |