Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cysteinyl leukotriene receptor 1
(GUINEA PIG) | BDBM50041342
(3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...)Show SMILES CCC(C)CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C31H35N3O5S/c1-6-20(2)18-32-30(35)23-13-14-27-26(16-23)25(19-34(27)4)15-22-11-12-24(17-28(22)39-5)31(36)33-40(37,38)29-10-8-7-9-21(29)3/h7-14,16-17,19-20H,6,15,18H2,1-5H3,(H,32,35)(H,33,36) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ICI Pharmaceuticals Group
Curated by ChEMBL
| Assay Description Binding affinity to the leukotriene receptor (LTD4) from guinea pig lung parenchymal membranes assayed using [3H]LTD4 as radioligand |
J Med Chem 36: 394-409 (1993)
Article DOI: 10.1021/jm00055a011 BindingDB Entry DOI: 10.7270/Q2FX7D5T |
More data for this Ligand-Target Pair | |
Cysteinyl leukotriene receptor 1
(GUINEA PIG) | BDBM50041342
(3-[2-Methoxy-4-(toluene-2-sulfonylaminocarbonyl)-b...)Show SMILES CCC(C)CNC(=O)c1ccc2n(C)cc(Cc3ccc(cc3OC)C(=O)NS(=O)(=O)c3ccccc3C)c2c1 Show InChI InChI=1S/C31H35N3O5S/c1-6-20(2)18-32-30(35)23-13-14-27-26(16-23)25(19-34(27)4)15-22-11-12-24(17-28(22)39-5)31(36)33-40(37,38)29-10-8-7-9-21(29)3/h7-14,16-17,19-20H,6,15,18H2,1-5H3,(H,32,35)(H,33,36) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
ZENECA Pharmaceuticals Group
Curated by ChEMBL
| Assay Description Inhibition constant for displacement of [3H]-LTD4 on guinea pig lung parenchymal membranes |
J Med Chem 37: 1282-97 (1994)
BindingDB Entry DOI: 10.7270/Q2SN0812 |
More data for this Ligand-Target Pair | |