Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protease
(Human immunodeficiency virus 1 (HIV-1)) | BDBM50479601
(CHEMBL507784)Show SMILES CCCCCCC(=O)N[C@@H](CSCCOCCOCCSC[C@H](NC(=O)CCCCCC)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C50H78N6O10S2/c1-5-8-10-18-24-43(57)52-41(47(60)55-40(50(63)64)33-38-22-16-13-17-23-38)34-67-30-28-65-26-27-66-29-31-68-35-42(53-44(58)25-19-11-9-6-2)48(61)56-45(36(4)7-3)49(62)54-39(46(51)59)32-37-20-14-12-15-21-37/h12-17,20-23,36,39-42,45H,5-11,18-19,24-35H2,1-4H3,(H2,51,59)(H,52,57)(H,53,58)(H,54,62)(H,55,60)(H,56,61)(H,63,64)/t36-,39+,40+,41+,42+,45+/m1/s1 | PDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 5.10E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Inhibition of HIV1 protease dimerization by Zhang-Poorman kinetic assay |
Bioorg Med Chem 17: 967-76 (2009)
Article DOI: 10.1016/j.bmc.2008.02.060
BindingDB Entry DOI: 10.7270/Q2QN69K9 |
More data for this
Ligand-Target Pair | |
Protease
(Human immunodeficiency virus 1 (HIV-1)) | BDBM50479601
(CHEMBL507784)Show SMILES CCCCCCC(=O)N[C@@H](CSCCOCCOCCSC[C@H](NC(=O)CCCCCC)C(=O)N[C@@H]([C@H](C)CC)C(=O)N[C@@H](Cc1ccccc1)C(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(O)=O |r| Show InChI InChI=1S/C50H78N6O10S2/c1-5-8-10-18-24-43(57)52-41(47(60)55-40(50(63)64)33-38-22-16-13-17-23-38)34-67-30-28-65-26-27-66-29-31-68-35-42(53-44(58)25-19-11-9-6-2)48(61)56-45(36(4)7-3)49(62)54-39(46(51)59)32-37-20-14-12-15-21-37/h12-17,20-23,36,39-42,45H,5-11,18-19,24-35H2,1-4H3,(H2,51,59)(H,52,57)(H,53,58)(H,54,62)(H,55,60)(H,56,61)(H,63,64)/t36-,39+,40+,41+,42+,45+/m1/s1 | PDB
UniProtKB/TrEMBL
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Purdue University
Curated by ChEMBL
| Assay Description
Inhibition of HIV1 protease by continuous fluorometric assay |
Bioorg Med Chem 17: 967-76 (2009)
Article DOI: 10.1016/j.bmc.2008.02.060
BindingDB Entry DOI: 10.7270/Q2QN69K9 |
More data for this
Ligand-Target Pair | |