Found 6 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysophosphatidic acid receptor 6
(Homo sapiens (Human)) | BDBM50430010
(CHEMBL2335047)Show SMILES CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC |r| Show InChI InChI=1S/C22H47O5PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26-20-22(25-2)21-27-28(23,24)29/h22H,3-21H2,1-2H3,(H2,23,24,29)/t22-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 90 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description Agonist activity at human LPA6 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 5
(Homo sapiens (Human)) | BDBM50430010
(CHEMBL2335047)Show SMILES CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC |r| Show InChI InChI=1S/C22H47O5PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26-20-22(25-2)21-27-28(23,24)29/h22H,3-21H2,1-2H3,(H2,23,24,29)/t22-/m0/s1 | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description Agonist activity at human LPA5 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM50430010
(CHEMBL2335047)Show SMILES CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC |r| Show InChI InChI=1S/C22H47O5PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26-20-22(25-2)21-27-28(23,24)29/h22H,3-21H2,1-2H3,(H2,23,24,29)/t22-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description Agonist activity at human LPA1 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 3
(Homo sapiens (Human)) | BDBM50430010
(CHEMBL2335047)Show SMILES CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC |r| Show InChI InChI=1S/C22H47O5PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26-20-22(25-2)21-27-28(23,24)29/h22H,3-21H2,1-2H3,(H2,23,24,29)/t22-/m0/s1 | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 0.370 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description Agonist activity at human LPA3 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 2
(Homo sapiens (Human)) | BDBM50430010
(CHEMBL2335047)Show SMILES CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC |r| Show InChI InChI=1S/C22H47O5PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26-20-22(25-2)21-27-28(23,24)29/h22H,3-21H2,1-2H3,(H2,23,24,29)/t22-/m0/s1 | NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description Agonist activity at human LPA2 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 4
(Homo sapiens (Human)) | BDBM50430010
(CHEMBL2335047)Show SMILES CCCCCCCCCCCCCCCCCCOC[C@@H](COP(O)(O)=S)OC |r| Show InChI InChI=1S/C22H47O5PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-26-20-22(25-2)21-27-28(23,24)29/h22H,3-21H2,1-2H3,(H2,23,24,29)/t22-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.5 | n/a | n/a | n/a | n/a |
The University of Utah
Curated by ChEMBL
| Assay Description Agonist activity at human LPA4 receptor transfected in HEK293 cells after 1 hr by TGFalpha shedding assay in presence of Ki16425 |
Bioorg Med Chem Lett 23: 1865-9 (2013)
Article DOI: 10.1016/j.bmcl.2013.01.002 BindingDB Entry DOI: 10.7270/Q2SN0B9G |
More data for this Ligand-Target Pair | |