Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carnitine O-palmitoyltransferase 1, liver isoform
(Rattus norvegicus) | BDBM50101600
(CHEMBL305897 | [3-Carboxy-2-(undecane-1-sulfamoyla...)Show SMILES CCCCCCCCCCCNS(=O)(=O)N[C@@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C18H39N3O4S/c1-5-6-7-8-9-10-11-12-13-14-19-26(24,25)20-17(15-18(22)23)16-21(2,3)4/h17,19-20H,5-16H2,1-4H3/t17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma Tau Pharmaceutical Industries S.p.A.
Curated by ChEMBL
| Assay Description Inhibition of rat liver mitochondrial carnitine palmitoyltransferase 1 using [14C]-palmitoyl-CoA radioligand |
J Med Chem 44: 2383-6 (2001)
BindingDB Entry DOI: 10.7270/Q2930SG7 |
More data for this Ligand-Target Pair | |
Carnitine O-palmitoyltransferase 1, liver isoform
(Rattus norvegicus) | BDBM50101600
(CHEMBL305897 | [3-Carboxy-2-(undecane-1-sulfamoyla...)Show SMILES CCCCCCCCCCCNS(=O)(=O)N[C@@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C18H39N3O4S/c1-5-6-7-8-9-10-11-12-13-14-19-26(24,25)20-17(15-18(22)23)16-21(2,3)4/h17,19-20H,5-16H2,1-4H3/t17-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma Tau Pharmaceutical Industries S.p.A.
Curated by ChEMBL
| Assay Description Inhibition of [14C]-palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I from rat liver mitochondria |
J Med Chem 46: 303-9 (2003)
Article DOI: 10.1021/jm020979u BindingDB Entry DOI: 10.7270/Q2N015WM |
More data for this Ligand-Target Pair | |
Carnitine O-palmitoyltransferase 1, muscle isoform
(Rattus norvegicus) | BDBM50101600
(CHEMBL305897 | [3-Carboxy-2-(undecane-1-sulfamoyla...)Show SMILES CCCCCCCCCCCNS(=O)(=O)N[C@@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C18H39N3O4S/c1-5-6-7-8-9-10-11-12-13-14-19-26(24,25)20-17(15-18(22)23)16-21(2,3)4/h17,19-20H,5-16H2,1-4H3/t17-/m0/s1 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma Tau Pharmaceutical Industries S.p.A.
Curated by ChEMBL
| Assay Description In vitro inhibition of [14C]-palmitoyl-CoA and carnitine binding to carnitine palmitoyltransferase I of rat heart mitochondria |
J Med Chem 46: 303-9 (2003)
Article DOI: 10.1021/jm020979u BindingDB Entry DOI: 10.7270/Q2N015WM |
More data for this Ligand-Target Pair | |
Carnitine O-palmitoyltransferase 1, muscle isoform
(Rattus norvegicus) | BDBM50101600
(CHEMBL305897 | [3-Carboxy-2-(undecane-1-sulfamoyla...)Show SMILES CCCCCCCCCCCNS(=O)(=O)N[C@@H](CC([O-])=O)C[N+](C)(C)C Show InChI InChI=1S/C18H39N3O4S/c1-5-6-7-8-9-10-11-12-13-14-19-26(24,25)20-17(15-18(22)23)16-21(2,3)4/h17,19-20H,5-16H2,1-4H3/t17-/m0/s1 | Reactome pathway
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sigma Tau Pharmaceutical Industries S.p.A.
Curated by ChEMBL
| Assay Description Inhibitory activity against rat heart mitochondrial carnitine palmitoyltransferase 1b using [14C]-palmitoyl-CoA as radioligand |
J Med Chem 44: 2383-6 (2001)
BindingDB Entry DOI: 10.7270/Q2930SG7 |
More data for this Ligand-Target Pair | |