Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
(Homo sapiens (Human)) | BDBM201408
(US9187424, 174)Show SMILES CCCCCCCCNC(=O)C1(C)CC(=C(C(=O)Nc2ccc(OC)cc2)C(=O)N1)c1ccc(C)cc1 |t:14| Show InChI InChI=1S/C30H39N3O4/c1-5-6-7-8-9-10-19-31-29(36)30(3)20-25(22-13-11-21(2)12-14-22)26(28(35)33-30)27(34)32-23-15-17-24(37-4)18-16-23/h11-18H,5-10,19-20H2,1-4H3,(H,31,36)(H,32,34)(H,33,35) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff... |
US Patent US9187424 (2015)
BindingDB Entry DOI: 10.7270/Q2FQ9VFG |
More data for this
Ligand-Target Pair | |
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
(Homo sapiens (Human)) | BDBM201408
(US9187424, 174)Show SMILES CCCCCCCCNC(=O)C1(C)CC(=C(C(=O)Nc2ccc(OC)cc2)C(=O)N1)c1ccc(C)cc1 |t:14| Show InChI InChI=1S/C30H39N3O4/c1-5-6-7-8-9-10-19-31-29(36)30(3)20-25(22-13-11-21(2)12-14-22)26(28(35)33-30)27(34)32-23-15-17-24(37-4)18-16-23/h11-18H,5-10,19-20H2,1-4H3,(H,31,36)(H,32,34)(H,33,35) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 237 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
MGAT2 enzyme was assayed using membranes isolated from Sf9 cells expressing the recombinant human MGAT2 cDNA with 2-monooleoylglycerol and [3H]-oleoy... |
US Patent US9187424 (2015)
BindingDB Entry DOI: 10.7270/Q2FQ9VFG |
More data for this
Ligand-Target Pair | |