Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human)) | BDBM50238298
(CHEMBL4074755)Show SMILES CCCCCCNC(=O)Nc1ccc(cc1)-c1ccnc2[nH]nc(C)c12 Show InChI InChI=1S/C20H25N5O/c1-3-4-5-6-12-22-20(26)23-16-9-7-15(8-10-16)17-11-13-21-19-18(17)14(2)24-25-19/h7-11,13H,3-6,12H2,1-2H3,(H,21,24,25)(H2,22,23,26) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology
Curated by ChEMBL
| Assay Description In vitro inhibitory activity against Angiotensin I converting enzyme |
J Med Chem 60: 5099-5119 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD |
More data for this Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM50238298
(CHEMBL4074755)Show SMILES CCCCCCNC(=O)Nc1ccc(cc1)-c1ccnc2[nH]nc(C)c12 Show InChI InChI=1S/C20H25N5O/c1-3-4-5-6-12-22-20(26)23-16-9-7-15(8-10-16)17-11-13-21-19-18(17)14(2)24-25-19/h7-11,13H,3-6,12H2,1-2H3,(H,21,24,25)(H2,22,23,26) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ... |
J Med Chem 60: 5099-5119 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD |
More data for this Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50238298
(CHEMBL4074755)Show SMILES CCCCCCNC(=O)Nc1ccc(cc1)-c1ccnc2[nH]nc(C)c12 Show InChI InChI=1S/C20H25N5O/c1-3-4-5-6-12-22-20(26)23-16-9-7-15(8-10-16)17-11-13-21-19-18(17)14(2)24-25-19/h7-11,13H,3-6,12H2,1-2H3,(H,21,24,25)(H2,22,23,26) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
East China University of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of VEGFR2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of A... |
J Med Chem 60: 5099-5119 (2017)
Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD |
More data for this Ligand-Target Pair | |