Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 337.4 BDBM50238294

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50238294 (CHEMBL4063380) Show SMILES CCCCCNC(=O)Nc1ccc(cc1)-c1ccnc2[nH]nc(C)c12 Show InChI InChI=1S/C19H23N5O/c1-3-4-5-11-21-19(25)22-15-8-6-14(7-9-15)16-10-12-20-18-17(16)13(2)23-24-18/h6-10,12H,3-5,11H2,1-2H3,(H,20,23,24)(H2,21,22,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of cKIT (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of ATP...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50238294 (CHEMBL4063380) Show SMILES CCCCCNC(=O)Nc1ccc(cc1)-c1ccnc2[nH]nc(C)c12 Show InChI InChI=1S/C19H23N5O/c1-3-4-5-11-21-19(25)22-15-8-6-14(7-9-15)16-10-12-20-18-17(16)13(2)23-24-18/h6-10,12H,3-5,11H2,1-2H3,(H,20,23,24)(H2,21,22,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence ...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50238294 (CHEMBL4063380) Show SMILES CCCCCNC(=O)Nc1ccc(cc1)-c1ccnc2[nH]nc(C)c12 Show InChI InChI=1S/C19H23N5O/c1-3-4-5-11-21-19(25)22-15-8-6-14(7-9-15)16-10-12-20-18-17(16)13(2)23-24-18/h6-10,12H,3-5,11H2,1-2H3,(H,20,23,24)(H2,21,22,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of VEGFR2 (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition in presence of A...				J Med Chem 60: 5099-5119 (2017) Article DOI: 10.1021/acs.jmedchem.7b00468 BindingDB Entry DOI: 10.7270/Q2JS9SPD
					More data for this Ligand-Target Pair