Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50231889
(3-(hydroxymethyl)-5-methyl-2-pentyl-1-phenethyl-1H...)Show SMILES CCCCCc1c(CO)c2cc(C)c(cc2n1CCc1ccccc1)C(O)=O Show InChI InChI=1S/C24H29NO3/c1-3-4-6-11-22-21(16-26)20-14-17(2)19(24(27)28)15-23(20)25(22)13-12-18-9-7-5-8-10-18/h5,7-10,14-15,26H,3-4,6,11-13,16H2,1-2H3,(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Binding affinity to GST tagged human beta 2 adrenergic receptor PDZ1 domain |
Bioorg Med Chem Lett 18: 942-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.038 BindingDB Entry DOI: 10.7270/Q2DJ5FC2 |
More data for this Ligand-Target Pair | |
Cystic fibrosis transmembrane conductance regulator
(Homo sapiens (Human)) | BDBM50231889
(3-(hydroxymethyl)-5-methyl-2-pentyl-1-phenethyl-1H...)Show SMILES CCCCCc1c(CO)c2cc(C)c(cc2n1CCc1ccccc1)C(O)=O Show InChI InChI=1S/C24H29NO3/c1-3-4-6-11-22-21(16-26)20-14-17(2)19(24(27)28)15-23(20)25(22)13-12-18-9-7-5-8-10-18/h5,7-10,14-15,26H,3-4,6,11-13,16H2,1-2H3,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.80E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Binding affinity to GST tagged human CFTR PDZ2 domain |
Bioorg Med Chem Lett 18: 942-5 (2008)
Article DOI: 10.1016/j.bmcl.2007.12.038 BindingDB Entry DOI: 10.7270/Q2DJ5FC2 |
More data for this Ligand-Target Pair | |