Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 409.8 BDBM251740

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM251740 (US10100018, Example 76 | US9464060, 76) Show SMILES CCN(Cc1ccc(cc1)C(O)=O)C(=O)c1ccc(Oc2ccccc2Cl)cc1 Show InChI InChI=1S/C23H20ClNO4/c1-2-25(15-16-7-9-18(10-8-16)23(27)28)22(26)17-11-13-19(14-12-17)29-21-6-4-3-5-20(21)24/h3-14H,2,15H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	37
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...				US Patent US9464060 (2016) BindingDB Entry DOI: 10.7270/Q23R0RT0
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM251740 (US10100018, Example 76 | US9464060, 76) Show SMILES CCN(Cc1ccc(cc1)C(O)=O)C(=O)c1ccc(Oc2ccccc2Cl)cc1 Show InChI InChI=1S/C23H20ClNO4/c1-2-25(15-16-7-9-18(10-8-16)23(27)28)22(26)17-11-13-19(14-12-17)29-21-6-4-3-5-20(21)24/h3-14H,2,15H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	25
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...				US Patent US10100018 (2018) BindingDB Entry DOI: 10.7270/Q2PR7Z0N
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 1 (Homo sapiens (Human))	BDBM251740 (US10100018, Example 76 | US9464060, 76) Show SMILES CCN(Cc1ccc(cc1)C(O)=O)C(=O)c1ccc(Oc2ccccc2Cl)cc1 Show InChI InChI=1S/C23H20ClNO4/c1-2-25(15-16-7-9-18(10-8-16)23(27)28)22(26)17-11-13-19(14-12-17)29-21-6-4-3-5-20(21)24/h3-14H,2,15H2,1H3,(H,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	25
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i...				US Patent US10100018 (2018) BindingDB Entry DOI: 10.7270/Q2PR7Z0N
					More data for this Ligand-Target Pair
Lysophosphatidic acid receptor 5 (Homo sapiens (Human))	BDBM251740 (US10100018, Example 76 | US9464060, 76) Show SMILES CCN(Cc1ccc(cc1)C(O)=O)C(=O)c1ccc(Oc2ccccc2Cl)cc1 Show InChI InChI=1S/C23H20ClNO4/c1-2-25(15-16-7-9-18(10-8-16)23(27)28)22(26)17-11-13-19(14-12-17)29-21-6-4-3-5-20(21)24/h3-14H,2,15H2,1H3,(H,27,28)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	37
Takeda Pharmaceutical Company Limited US Patent					Assay Description Engagement of the LPA5 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ...				US Patent US9464060 (2016) BindingDB Entry DOI: 10.7270/Q23R0RT0
					More data for this Ligand-Target Pair