Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-dependent kinase 4
(Homo sapiens (Human)) | BDBM419863
(US10464927, Compound I-11)Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3ncnc4n(C5CCCC5)c(C)cc34)nc2)CC1 Show InChI InChI=1S/C28H34FN9/c1-3-36-10-12-37(13-11-36)17-20-8-9-24(30-15-20)34-28-31-16-23(29)26(35-28)25-22-14-19(2)38(21-6-4-5-7-21)27(22)33-18-32-25/h8-9,14-16,18,21H,3-7,10-13,17H2,1-2H3,(H,30,31,34,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <20 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Xunhe Pharmaceutical Technology Co. Ltd.
US Patent
| Assay Description
CDK4: The test compound was dissolved in DMSO and diluted with a kinase buffer solution (20 mM HEPES-pH 7.5, 0.01% Triton X-100, 10 mM MgCl2, 2 mM DT... |
US Patent US10464927 (2019)
BindingDB Entry DOI: 10.7270/Q23B62GC |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 6
(Homo sapiens (Human)) | BDBM419863
(US10464927, Compound I-11)Show SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3ncnc4n(C5CCCC5)c(C)cc34)nc2)CC1 Show InChI InChI=1S/C28H34FN9/c1-3-36-10-12-37(13-11-36)17-20-8-9-24(30-15-20)34-28-31-16-23(29)26(35-28)25-22-14-19(2)38(21-6-4-5-7-21)27(22)33-18-32-25/h8-9,14-16,18,21H,3-7,10-13,17H2,1-2H3,(H,30,31,34,35) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Xunhe Pharmaceutical Technology Co. Ltd.
US Patent
| Assay Description
CDK6: The test compound was dissolved in DMSO and diluted with a kinase buffer solution (20 mM HEPES-pH 7.5, 0.01% Triton X-100, 10 mM MgCl2, 2 mM D... |
US Patent US10464927 (2019)
BindingDB Entry DOI: 10.7270/Q23B62GC |
More data for this
Ligand-Target Pair | |