Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 609.5 BDBM201487

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM201487 (US9187424, 254) Show SMILES CCNC(=O)NC1=C(CC(NC1=O)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)c1ccc(OCC(F)F)cc1 |t:6| Show InChI InChI=1S/C27H27F8N3O4/c1-2-36-24(40)37-22-20(16-4-8-19(9-5-16)42-15-21(28)29)14-25(27(33,34)35,38-23(22)39)17-6-10-18(11-7-17)41-13-3-12-26(30,31)32/h4-11,21H,2-3,12-15H2,1H3,(H,38,39)(H2,36,37,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	7.4	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The MGAT enzyme reactions were performed in CORNING Falcon 96-well Polypropylene plates, in a total volume of 60 uL of 50 mM Potassium Phosphate buff...				US Patent US9187424 (2015) BindingDB Entry DOI: 10.7270/Q2FQ9VFG
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