Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 390.4 BDBM50024691

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50024691 (5-[2-Imidazol-1-yl-1-(4-methoxy-benzyloxymethyl)-e...) Show SMILES CCOC(=O)CCCCOC(COCc1ccc(OC)cc1)Cn1ccnc1 Show InChI InChI=1S/C21H30N2O5/c1-3-27-21(24)6-4-5-13-28-20(14-23-12-11-22-17-23)16-26-15-18-7-9-19(25-2)10-8-18/h7-12,17,20H,3-6,13-16H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Searle Research and Development Curated by ChEMBL					Assay Description Inhibition of Thromboxane B2 formation in collagen-stimulated human platelets in platelet rich plasma.				J Med Chem 30: 1812-8 (1987) BindingDB Entry DOI: 10.7270/Q2ZP454K
					More data for this Ligand-Target Pair