Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 424.5 BDBM50121019

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM50121019 (({1-[2-(4-Benzyl-phenoxy)-ethyl]-piperidine-4-carb...) Show SMILES CCOC(=O)CNC(=O)C1CCN(CCOc2ccc(Cc3ccccc3)cc2)CC1 Show InChI InChI=1S/C25H32N2O4/c1-2-30-24(28)19-26-25(29)22-12-14-27(15-13-22)16-17-31-23-10-8-21(9-11-23)18-20-6-4-3-5-7-20/h3-11,22H,2,12-19H2,1H3,(H,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation Curated by ChEMBL					Assay Description Inhibition of leukotriene A4 hydrolase in human recombinant assay				Bioorg Med Chem Lett 12: 3383-6 (2002) BindingDB Entry DOI: 10.7270/Q2N8795W
					More data for this Ligand-Target Pair