Found 8 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
X-box-binding protein 1
(Homo sapiens (Human)) | BDBM38845
(MLS000032332 | N-[4-(2-{5-[(4-Chloro-phenylamino)-...)Show SMILES CCOc1cc(ccc1NC(=O)CC)C(=O)CSc1nnc(CNc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H23ClN4O4S/c1-3-20(29)25-17-10-5-14(11-19(17)30-4-2)18(28)13-32-22-27-26-21(31-22)12-24-16-8-6-15(23)7-9-16/h5-11,24H,3-4,12-13H2,1-2H3,(H,25,29) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | 6.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q2NK3CGB |
More data for this
Ligand-Target Pair | |
Steroidogenic factor 1
(Homo sapiens (Human)) | BDBM38845
(MLS000032332 | N-[4-(2-{5-[(4-Chloro-phenylamino)-...)Show SMILES CCOc1cc(ccc1NC(=O)CC)C(=O)CSc1nnc(CNc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H23ClN4O4S/c1-3-20(29)25-17-10-5-14(11-19(17)30-4-2)18(28)13-32-22-27-26-21(31-22)12-24-16-8-6-15(23)7-9-16/h5-11,24H,3-4,12-13H2,1-2H3,(H,25,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | 7.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... |
PubChem Bioassay (2007)
BindingDB Entry DOI: 10.7270/Q2PR7TCX |
More data for this
Ligand-Target Pair | |
Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2)
(Homo sapiens (Human)) | BDBM38845
(MLS000032332 | N-[4-(2-{5-[(4-Chloro-phenylamino)-...)Show SMILES CCOc1cc(ccc1NC(=O)CC)C(=O)CSc1nnc(CNc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H23ClN4O4S/c1-3-20(29)25-17-10-5-14(11-19(17)30-4-2)18(28)13-32-22-27-26-21(31-22)12-24-16-8-6-15(23)7-9-16/h5-11,24H,3-4,12-13H2,1-2H3,(H,25,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | 7.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... |
PubChem Bioassay (2007)
BindingDB Entry DOI: 10.7270/Q2TH8K3N |
More data for this
Ligand-Target Pair | |
Steroidogenic factor 1
(Homo sapiens (Human)) | BDBM38845
(MLS000032332 | N-[4-(2-{5-[(4-Chloro-phenylamino)-...)Show SMILES CCOc1cc(ccc1NC(=O)CC)C(=O)CSc1nnc(CNc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H23ClN4O4S/c1-3-20(29)25-17-10-5-14(11-19(17)30-4-2)18(28)13-32-22-27-26-21(31-22)12-24-16-8-6-15(23)7-9-16/h5-11,24H,3-4,12-13H2,1-2H3,(H,25,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | 8.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... |
PubChem Bioassay (2007)
BindingDB Entry DOI: 10.7270/Q2319T8T |
More data for this
Ligand-Target Pair | |
Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2)
(Homo sapiens (Human)) | BDBM38845
(MLS000032332 | N-[4-(2-{5-[(4-Chloro-phenylamino)-...)Show SMILES CCOc1cc(ccc1NC(=O)CC)C(=O)CSc1nnc(CNc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H23ClN4O4S/c1-3-20(29)25-17-10-5-14(11-19(17)30-4-2)18(28)13-32-22-27-26-21(31-22)12-24-16-8-6-15(23)7-9-16/h5-11,24H,3-4,12-13H2,1-2H3,(H,25,29) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | 8.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description
Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... |
PubChem Bioassay (2007)
BindingDB Entry DOI: 10.7270/Q26Q1VNZ |
More data for this
Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM38845
(MLS000032332 | N-[4-(2-{5-[(4-Chloro-phenylamino)-...)Show SMILES CCOc1cc(ccc1NC(=O)CC)C(=O)CSc1nnc(CNc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H23ClN4O4S/c1-3-20(29)25-17-10-5-14(11-19(17)30-4-2)18(28)13-32-22-27-26-21(31-22)12-24-16-8-6-15(23)7-9-16/h5-11,24H,3-4,12-13H2,1-2H3,(H,25,29) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2PC30VZ |
More data for this
Ligand-Target Pair | |
DNA damage-inducible transcript 3 protein
(Mus musculus) | BDBM38845
(MLS000032332 | N-[4-(2-{5-[(4-Chloro-phenylamino)-...)Show SMILES CCOc1cc(ccc1NC(=O)CC)C(=O)CSc1nnc(CNc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H23ClN4O4S/c1-3-20(29)25-17-10-5-14(11-19(17)30-4-2)18(28)13-32-22-27-26-21(31-22)12-24-16-8-6-15(23)7-9-16/h5-11,24H,3-4,12-13H2,1-2H3,(H,25,29) | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center
Curated by PubChem BioAssay
| Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer... |
PubChem Bioassay (2011)
BindingDB Entry DOI: 10.7270/Q28C9TQN |
More data for this
Ligand-Target Pair | |
Bcl-2-like protein 11
(Homo sapiens (Human)) | BDBM38845
(MLS000032332 | N-[4-(2-{5-[(4-Chloro-phenylamino)-...)Show SMILES CCOc1cc(ccc1NC(=O)CC)C(=O)CSc1nnc(CNc2ccc(Cl)cc2)o1 Show InChI InChI=1S/C22H23ClN4O4S/c1-3-20(29)25-17-10-5-14(11-19(17)30-4-2)18(28)13-32-22-27-26-21(31-22)12-24-16-8-6-15(23)7-9-16/h5-11,24H,3-4,12-13H2,1-2H3,(H,25,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| PCBioAssay
| n/a | n/a | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a |
Broad Institute
Curated by PubChem BioAssay
| Assay Description
Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q24J0CKJ |
More data for this
Ligand-Target Pair | |