Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50508142
(CHEMBL4452945)Show SMILES CCOc1ccc(cc1CC(O)=O)-c1ccc(CCCc2nn(-c3ccc(cc3)C(F)(F)F)c(=O)n2-c2ccccc2C(F)(F)F)cc1 |(51.28,-22.26,;49.96,-23.05,;48.62,-22.29,;47.29,-23.08,;45.94,-22.32,;44.62,-23.11,;44.64,-24.63,;45.98,-25.4,;47.31,-24.62,;48.65,-25.38,;48.66,-26.92,;47.33,-27.7,;50,-27.67,;43.32,-25.42,;43.33,-26.96,;42,-27.74,;40.66,-26.97,;39.33,-27.76,;37.99,-27,;36.67,-27.78,;35.33,-27.02,;34.85,-25.56,;33.31,-25.56,;32.53,-24.23,;33.29,-22.9,;32.51,-21.57,;30.97,-21.58,;30.21,-22.93,;31,-24.25,;30.19,-20.26,;30.94,-18.92,;28.65,-20.27,;29.4,-18.92,;32.84,-27.03,;31.37,-27.51,;34.09,-27.92,;34.09,-29.46,;32.76,-30.23,;32.77,-31.76,;34.1,-32.53,;35.43,-31.76,;35.44,-30.22,;36.77,-29.44,;37.52,-28.1,;38.09,-30.21,;38.24,-29.04,;40.65,-25.44,;41.97,-24.66,)| Show InChI InChI=1S/C35H29F6N3O4/c1-2-48-30-19-14-24(20-25(30)21-32(45)46)23-12-10-22(11-13-23)6-5-9-31-42-44(27-17-15-26(16-18-27)34(36,37)38)33(47)43(31)29-8-4-3-7-28(29)35(39,40)41/h3-4,7-8,10-20H,2,5-6,9,21H2,1H3,(H,45,46) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 433 | n/a | n/a | n/a | n/a | n/a | n/a |
Inception Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human PPARalpha assessed as inhibition of GW7647-induced receptor activation after overnight incubation by cell-ba... |
Bioorg Med Chem Lett 29: 503-508 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.045
BindingDB Entry DOI: 10.7270/Q2XK8JVQ |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50508142
(CHEMBL4452945)Show SMILES CCOc1ccc(cc1CC(O)=O)-c1ccc(CCCc2nn(-c3ccc(cc3)C(F)(F)F)c(=O)n2-c2ccccc2C(F)(F)F)cc1 |(51.28,-22.26,;49.96,-23.05,;48.62,-22.29,;47.29,-23.08,;45.94,-22.32,;44.62,-23.11,;44.64,-24.63,;45.98,-25.4,;47.31,-24.62,;48.65,-25.38,;48.66,-26.92,;47.33,-27.7,;50,-27.67,;43.32,-25.42,;43.33,-26.96,;42,-27.74,;40.66,-26.97,;39.33,-27.76,;37.99,-27,;36.67,-27.78,;35.33,-27.02,;34.85,-25.56,;33.31,-25.56,;32.53,-24.23,;33.29,-22.9,;32.51,-21.57,;30.97,-21.58,;30.21,-22.93,;31,-24.25,;30.19,-20.26,;30.94,-18.92,;28.65,-20.27,;29.4,-18.92,;32.84,-27.03,;31.37,-27.51,;34.09,-27.92,;34.09,-29.46,;32.76,-30.23,;32.77,-31.76,;34.1,-32.53,;35.43,-31.76,;35.44,-30.22,;36.77,-29.44,;37.52,-28.1,;38.09,-30.21,;38.24,-29.04,;40.65,-25.44,;41.97,-24.66,)| Show InChI InChI=1S/C35H29F6N3O4/c1-2-48-30-19-14-24(20-25(30)21-32(45)46)23-12-10-22(11-13-23)6-5-9-31-42-44(27-17-15-26(16-18-27)34(36,37)38)33(47)43(31)29-8-4-3-7-28(29)35(39,40)41/h3-4,7-8,10-20H,2,5-6,9,21H2,1H3,(H,45,46) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 515 | n/a | n/a | n/a | n/a | n/a | n/a |
Inception Sciences
Curated by ChEMBL
| Assay Description
Antagonist activity at recombinant human PPARdelta assessed as inhibition of GW0742-induced receptor activation after overnight incubation by cell-ba... |
Bioorg Med Chem Lett 29: 503-508 (2019)
Article DOI: 10.1016/j.bmcl.2018.12.045
BindingDB Entry DOI: 10.7270/Q2XK8JVQ |
More data for this
Ligand-Target Pair | |