Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Uncharacterized protein
(Cryptosporidium parvum) | BDBM286305
(5-amino-3-(2-ethoxyquinolin-6- yl)-1-(3-hydroxy-3-...)Show SMILES CCOc1ccc2cc(ccc2n1)-c1nn(C(C)C(C)(C)O)c(N)c1C(N)=O Show InChI InChI=1S/C20H25N5O3/c1-5-28-15-9-7-12-10-13(6-8-14(12)23-15)17-16(19(22)26)18(21)25(24-17)11(2)20(3,4)27/h6-11,27H,5,21H2,1-4H3,(H2,22,26) | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286305
(5-amino-3-(2-ethoxyquinolin-6- yl)-1-(3-hydroxy-3-...)Show SMILES CCOc1ccc2cc(ccc2n1)-c1nn(C(C)C(C)(C)O)c(N)c1C(N)=O Show InChI InChI=1S/C20H25N5O3/c1-5-28-15-9-7-12-10-13(6-8-14(12)23-15)17-16(19(22)26)18(21)25(24-17)11(2)20(3,4)27/h6-11,27H,5,21H2,1-4H3,(H2,22,26) | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Washington Through its Center For Commercialization
US Patent
| Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
US Patent US9518026 (2016)
BindingDB Entry DOI: 10.7270/Q2BV7JN4 |
More data for this Ligand-Target Pair | |
Calcium-dependent protein kinase 1
(Cryptosporidium parvum) | BDBM286305
(5-amino-3-(2-ethoxyquinolin-6- yl)-1-(3-hydroxy-3-...)Show SMILES CCOc1ccc2cc(ccc2n1)-c1nn(C(C)C(C)(C)O)c(N)c1C(N)=O Show InChI InChI=1S/C20H25N5O3/c1-5-28-15-9-7-12-10-13(6-8-14(12)23-15)17-16(19(22)26)18(21)25(24-17)11(2)20(3,4)27/h6-11,27H,5,21H2,1-4H3,(H2,22,26) | UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this Ligand-Target Pair | |
Calmodulin-domain protein kinase 1
(Toxoplasma gondii) | BDBM286305
(5-amino-3-(2-ethoxyquinolin-6- yl)-1-(3-hydroxy-3-...)Show SMILES CCOc1ccc2cc(ccc2n1)-c1nn(C(C)C(C)(C)O)c(N)c1C(N)=O Show InChI InChI=1S/C20H25N5O3/c1-5-28-15-9-7-12-10-13(6-8-14(12)23-15)17-16(19(22)26)18(21)25(24-17)11(2)20(3,4)27/h6-11,27H,5,21H2,1-4H3,(H2,22,26) | PDB
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim (Canada) Ltd.
| Assay Description Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti... |
Bioorg Med Chem Lett 19: 1199-205 (2009)
BindingDB Entry DOI: 10.7270/Q23J3G91 |
More data for this Ligand-Target Pair | |