Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase 8
(Homo sapiens (Human)) | BDBM15950
(Aminopyridine-Based Inhibitor 30 | N-(4-Amino-5-cy...)Show InChI InChI=1S/C14H19N5O3/c1-2-22-14-10(8-15)11(16)7-12(18-14)17-13(20)9-19-3-5-21-6-4-19/h7H,2-6,9H2,1H3,(H3,16,17,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
| Assay Description In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm... |
J Med Chem 49: 3563-80 (2006)
Article DOI: 10.1021/jm060199b BindingDB Entry DOI: 10.7270/Q2P26WDX |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase 9
(Homo sapiens (Human)) | BDBM15950
(Aminopyridine-Based Inhibitor 30 | N-(4-Amino-5-cy...)Show InChI InChI=1S/C14H19N5O3/c1-2-22-14-10(8-15)11(16)7-12(18-14)17-13(20)9-19-3-5-21-6-4-19/h7H,2-6,9H2,1H3,(H3,16,17,18,20) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
| Assay Description In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm... |
J Med Chem 49: 3563-80 (2006)
Article DOI: 10.1021/jm060199b BindingDB Entry DOI: 10.7270/Q2P26WDX |
More data for this Ligand-Target Pair | |