Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50371511
(CHEMBL272720)Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc(cn1-c1ccc(cc1)C#N)-c1cccnc1)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C30H27F4N5O3S/c1-3-43(41,42)14-13-38(28(40)16-22-8-11-26(31)25(15-22)30(32,33)34)20(2)29-37-27(23-5-4-12-36-18-23)19-39(29)24-9-6-21(17-35)7-10-24/h4-12,15,18-20H,3,13-14,16H2,1-2H3/t20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC |
Bioorg Med Chem Lett 18: 608-13 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.072
BindingDB Entry DOI: 10.7270/Q2668F1D |
More data for this
Ligand-Target Pair | |
C-X-C chemokine receptor type 3
(Homo sapiens (Human)) | BDBM50371511
(CHEMBL272720)Show SMILES CCS(=O)(=O)CCN([C@H](C)c1nc(cn1-c1ccc(cc1)C#N)-c1cccnc1)C(=O)Cc1ccc(F)c(c1)C(F)(F)F Show InChI InChI=1S/C30H27F4N5O3S/c1-3-43(41,42)14-13-38(28(40)16-22-8-11-26(31)25(15-22)30(32,33)34)20(2)29-37-27(23-5-4-12-36-18-23)19-39(29)24-9-6-21(17-35)7-10-24/h4-12,15,18-20H,3,13-14,16H2,1-2H3/t20-/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description
Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMC in presence of plasma |
Bioorg Med Chem Lett 18: 608-13 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.072
BindingDB Entry DOI: 10.7270/Q2668F1D |
More data for this
Ligand-Target Pair | |