Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM148237
(US8962630, 46)Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(C[C@@H](O)CO)CC3)nc2n1C1CCCC1 |r| Show InChI InChI=1S/C26H36N8O3/c1-31(2)25(37)22-13-18-14-28-26(30-24(18)34(22)19-5-3-4-6-19)29-23-8-7-20(15-27-23)33-11-9-32(10-12-33)16-21(36)17-35/h7-8,13-15,19,21,35-36H,3-6,9-12,16-17H2,1-2H3,(H,27,28,29,30)/t21-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG
US Patent
| Assay Description
The assay was run under the conditions identical to that for CDK1/cyclin B except 0.25 nM CDK1/cyclin B was replaced with 0.3 nM CDK2/cyclin A. A 384... |
US Patent US8962630 (2015)
BindingDB Entry DOI: 10.7270/Q2RJ4H6C |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 1
(Homo sapiens (Human)) | BDBM148237
(US8962630, 46)Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCN(C[C@@H](O)CO)CC3)nc2n1C1CCCC1 |r| Show InChI InChI=1S/C26H36N8O3/c1-31(2)25(37)22-13-18-14-28-26(30-24(18)34(22)19-5-3-4-6-19)29-23-8-7-20(15-27-23)33-11-9-32(10-12-33)16-21(36)17-35/h7-8,13-15,19,21,35-36H,3-6,9-12,16-17H2,1-2H3,(H,27,28,29,30)/t21-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| US Patent
| n/a | n/a | >1.50E+4 | n/a | n/a | n/a | n/a | n/a | 25 |
Novartis AG
US Patent
| Assay Description
A 384-well microtiter IMAP-FPT (Molecular Devices Trade Mark Technology) endpoint assay was used for CDK1/cyclin B kinase activity measurements. The ... |
US Patent US8962630 (2015)
BindingDB Entry DOI: 10.7270/Q2RJ4H6C |
More data for this
Ligand-Target Pair | |