Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 299.3 BDBM50511922

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50511922 (CHEMBL4539314) Show SMILES CN(CCO)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H21N3O2/c1-3-17(22)19-15-6-4-5-13(9-15)16-11-18-10-14(16)12-20(2)7-8-21/h3-6,9-11,18,21H,1,7-8,12H2,2H3,(H,19,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT6 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 6 (Homo sapiens (Human))	BDBM50511922 (CHEMBL4539314) Show SMILES CN(CCO)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H21N3O2/c1-3-17(22)19-15-6-4-5-13(9-15)16-11-18-10-14(16)12-20(2)7-8-21/h3-6,9-11,18,21H,1,7-8,12H2,2H3,(H,19,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT6 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 1 (Homo sapiens)	BDBM50511922 (CHEMBL4539314) Show SMILES CN(CCO)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H21N3O2/c1-3-17(22)19-15-6-4-5-13(9-15)16-11-18-10-14(16)12-20(2)7-8-21/h3-6,9-11,18,21H,1,7-8,12H2,2H3,(H,19,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT1 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 8 (Homo sapiens (Human))	BDBM50511922 (CHEMBL4539314) Show SMILES CN(CCO)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H21N3O2/c1-3-17(22)19-15-6-4-5-13(9-15)16-11-18-10-14(16)12-20(2)7-8-21/h3-6,9-11,18,21H,1,7-8,12H2,2H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT8 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Histone-arginine methyltransferase CARM1 (Homo sapiens (Human))	BDBM50511922 (CHEMBL4539314) Show SMILES CN(CCO)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H21N3O2/c1-3-17(22)19-15-6-4-5-13(9-15)16-11-18-10-14(16)12-20(2)7-8-21/h3-6,9-11,18,21H,1,7-8,12H2,2H3,(H,19,22)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT4 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair
Protein arginine N-methyltransferase 3 (Homo sapiens)	BDBM50511922 (CHEMBL4539314) Show SMILES CN(CCO)Cc1c[nH]cc1-c1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C17H21N3O2/c1-3-17(22)19-15-6-4-5-13(9-15)16-11-18-10-14(16)12-20(2)7-8-21/h3-6,9-11,18,21H,1,7-8,12H2,2H3,(H,19,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human PRMT3 using [3H]SAM as donor and [3H]methylated biotin-labeled peptide as substrate by scintillation proximity assay				J Med Chem 63: 5477-5487 (2020) Article DOI: 10.1021/acs.jmedchem.0c00406 BindingDB Entry DOI: 10.7270/Q2BG2S9V
					More data for this Ligand-Target Pair