SMILES String Search

Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 491.5
BDBM50510133

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 39 hits in this display
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused FGFR3 C-terminal domain (R397 to T806 residues) expressed in Sf9 insect cells usi...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
BDNF/NT-3 growth factors receptor (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-His6-fused TRKB C-terminal domain (V526 to G838 residues) expressed in Sf9 insect cells using Poly(Glu...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
SRSF protein kinase 1 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-His6-fused SRPK1 (M1 to S655 residues) expressed in Sf9 insect cells using RS-peptide as s...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-4 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-His6-fused ERBB4 C-terminal domain (R676 to V1307 residues) expressed in Sf9 cells using Poly(Glu:Tyr)...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-His6-fused SRC (M1 to L536 residues) expressed in Sf9 insect cells using Poly(Glu:Tyr)4:1 ...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused EGFR C-terminal domain (H672 to A1210) expressed in Sf9 insect cells using Poly(G...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 4 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-His6-fused FGFR4 (R391 to T802 residues) expressed in baculovirus infected Sf9 cells using Poly(Glu:Ty...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-fused PDK1 (M1 to M460 residues) expressed in Sf9 insect cells using tetra(LRRWSLG) peptide as substr...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused KIT C-terminal domain (T544 to V976 residues) expressed in Sf9 insect cells using...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused FGFR1 C-terminal domain (G400 to R820 residues) expressed in Sf9 insect cells usi...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK1 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-His6-fused CLK1 (M1 to I484 residues) expressed in Sf9 cells using RS-peptide as substrate...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused TRKA C-terminal domain (G443 to G796 residues) expressed in Sf9 insect cells usin...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 10 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human MAP3K10 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting method				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-His6-fused AKT2 C-terminal domain (A107 to E481 residues) expressed in Sf9 insect cells using GSK3(14-...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-His6-fused FGFR2 C-terminal domain (R400 to T822 residues) expressed in Sf9 insect cells using TRK-C d...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused ERBB2 C-terminal domain (Q679 to V1255 residues) expressed in Sf9 insect cells us...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-fused VEGFR2 C-terminal domain (D807 to V1356 residues) expressed in Sf9 insect cells using Poly(Glu:T...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human ROCK1 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting method				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged VEGFR1 C-terminal domain (K784 to I1338 residues) expressed in Sf9 insect cells using Poly(Glu:...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused PDGFR-alpha C-terminal domain (Q551 to L1089 residues) expressed in Sf9 insect ce...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused MET C-terminal domain (K956 to S1390 residues) expressed in Sf9 insect cells usin...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 15 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal 4xFLAG-tagged/C-terminal His8-fused ERK7 N-terminal domain (M1 to R354 residues) expressed in Sf9 insect c...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-His6 fused ERK1 (M1 to P379 residues) expressed in Escherichia coli using RBER-CHKtide as ...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 1 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal 4xFLAG-tagged/C-terminal His8 fused MAP3K1 C-terminal domain (M1193 to W1512 residues) expressed in Sf9 in...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length untagged ERK2 (M1 to S360 residues) expressed in Escherichia coli using recombinant ELK1 as substrate mea...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human wild-type N-terminal GST-His6-fused ABL1 internal domain (P118 to S535 residues) expressed in Sf9 insect cells using ...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 2 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human MEK2 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting method				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human CHK2 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting method				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Wee1-like protein kinase (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-His6-fused WEE1 C-terminal domain (Q36 to Y432 residues) expressed in Sf9 cells using Poly(Ala,Glu,Lys...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-His6-fused PDGFR-beta C-terminal domain (R561 to L1106 residues) expressed in Sf9 insect cells using P...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length untagged p38-alpha (M1 to S360 residues) expressed in Escherichia coli cells using recombinant ATF2 as su...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 7 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal FLAG-tagged/C-terminal His8 fused ERK5 internal fragment domain (L5 to Q397 residues) expressed in Sf9 ins...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha' (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-His6-fused CK2-alpha2 (M1 to R350 residues) expressed in Sf9 insect cells using casein as ...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-fused FAK (2 to 1052 residues) expressed in Sf9 insect cells using Poly(Glu/Tyr)4:1 as substrate measu...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-His6 fused VEGFR3 C-terminal domain (N799 to R1298 residues) expressed in baculovirus infected Sf9 ins...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 9 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human MAP3K9 measured after 60 mins in presence of [gamma-33P]-ATP by scintillation counting method				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human wild-type full-length MEK1 (M1 to V393 residues) expressed in Sf9 insect cells using ERK2-K54R as substrate measured ...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
RAC-beta serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-His6-fused AKT2 (M1 to E481 residues) expressed in Sf9 insect cells using GSK3-derived pep...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50510133 (CHEMBL4446681) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Naples Federico II Curated by ChEMBL					Assay Description Inhibition of recombinant human full-length N-terminal GST-fused CK2-alpha1 (M1 to Q391 residues) expressed in Sf9 insect cells using casein as subst...				Eur J Med Chem 167: 61-75 (2019) Article DOI: 10.1016/j.ejmech.2019.01.066 BindingDB Entry DOI: 10.7270/Q2FT8QB4
University of Naples Federico II Curated by ChEMBL					More data for this Ligand-Target Pair