Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM150647
(US10238633, Example 321 | US8987249, 321 | US97136...)Show SMILES CN1CCC(C)(CC1)c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C23H31FN4O/c1-23(7-9-28(2)10-8-23)17-5-3-15(20(24)13-17)11-19(14-25)27-22(29)21-16-4-6-18(12-16)26-21/h3,5,13,16,18-19,21,26H,4,6-12H2,1-2H3,(H,27,29)/t16-,18+,19-,21-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 56.8 | n/a | n/a | n/a | n/a | n/a | 25 |
Boehringer Ingelheim International GmbH
US Patent
| Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys... |
US Patent US8987249 (2015)
BindingDB Entry DOI: 10.7270/Q2KP80WG |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM150647
(US10238633, Example 321 | US8987249, 321 | US97136...)Show SMILES CN1CCC(C)(CC1)c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C23H31FN4O/c1-23(7-9-28(2)10-8-23)17-5-3-15(20(24)13-17)11-19(14-25)27-22(29)21-16-4-6-18(12-16)26-21/h3,5,13,16,18-19,21,26H,4,6-12H2,1-2H3,(H,27,29)/t16-,18+,19-,21-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 56.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation
| Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ... |
J Med Chem 50: 984-1000 (2007)
BindingDB Entry DOI: 10.7270/Q22R3TZF |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 1
(Homo sapiens (Human)) | BDBM150647
(US10238633, Example 321 | US8987249, 321 | US97136...)Show SMILES CN1CCC(C)(CC1)c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C23H31FN4O/c1-23(7-9-28(2)10-8-23)17-5-3-15(20(24)13-17)11-19(14-25)27-22(29)21-16-4-6-18(12-16)26-21/h3,5,13,16,18-19,21,26H,4,6-12H2,1-2H3,(H,27,29)/t16-,18+,19-,21-/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| US Patent
| n/a | n/a | 56.8 | n/a | n/a | n/a | n/a | 6.0 | 25 |
Boehringer Ingelheim International GmbH
US Patent
| Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 6007270). The substrate Gly-Arg-AMC was from Biotrend (Prod.... |
US Patent US9713606 (2017)
BindingDB Entry DOI: 10.7270/Q21G0P8M |
More data for this Ligand-Target Pair | |