Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1F
(Homo sapiens (Human)) | BDBM50130445
(CHEMBL105743 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccccc3)nc12 Show InChI InChI=1S/C20H22N4O/c1-24-11-9-14(10-12-24)16-13-21-17-7-8-18(22-19(16)17)23-20(25)15-5-3-2-4-6-15/h2-8,13-14,21H,9-12H2,1H3,(H,22,23,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 7.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptor |
J Med Chem 46: 3060-71 (2003)
Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50130445
(CHEMBL105743 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccccc3)nc12 Show InChI InChI=1S/C20H22N4O/c1-24-11-9-14(10-12-24)16-13-21-17-7-8-18(22-19(16)17)23-20(25)15-5-3-2-4-6-15/h2-8,13-14,21H,9-12H2,1H3,(H,22,23,25) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 72 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1A recepto... |
J Med Chem 46: 3060-71 (2003)
Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50130445
(CHEMBL105743 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccccc3)nc12 Show InChI InChI=1S/C20H22N4O/c1-24-11-9-14(10-12-24)16-13-21-17-7-8-18(22-19(16)17)23-20(25)15-5-3-2-4-6-15/h2-8,13-14,21H,9-12H2,1H3,(H,22,23,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 820 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1B recepto... |
J Med Chem 46: 3060-71 (2003)
Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50130445
(CHEMBL105743 | N-[3-(1-Methyl-piperidin-4-yl)-1H-p...)Show SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)c3ccccc3)nc12 Show InChI InChI=1S/C20H22N4O/c1-24-11-9-14(10-12-24)16-13-21-17-7-8-18(22-19(16)17)23-20(25)15-5-3-2-4-6-15/h2-8,13-14,21H,9-12H2,1H3,(H,22,23,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description In vitro binding affinity of the compound was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D recepto... |
J Med Chem 46: 3060-71 (2003)
Article DOI: 10.1021/jm030020m BindingDB Entry DOI: 10.7270/Q21V5DCB |
More data for this Ligand-Target Pair | |