Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50454687
(CHEMBL2112661)Show SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)N3CCN(CC3)c3cccc4ccccc34)cc12 Show InChI InChI=1S/C31H34N4O2/c1-32-14-16-33(17-15-32)30-11-5-8-25-12-13-26(22-28(25)30)37-23-31(36)35-20-18-34(19-21-35)29-10-4-7-24-6-2-3-9-27(24)29/h2-13,22H,14-21,23H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.430 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE
Curated by ChEMBL
| Assay Description Receptor binding affinity for cloned human 5-hydroxytryptamine 1B receptor in Cos-7 cells |
J Med Chem 40: 3974-8 (1998)
Article DOI: 10.1021/jm9703552 BindingDB Entry DOI: 10.7270/Q2FT8K57 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1D
(Homo sapiens (Human)) | BDBM50454687
(CHEMBL2112661)Show SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)N3CCN(CC3)c3cccc4ccccc34)cc12 Show InChI InChI=1S/C31H34N4O2/c1-32-14-16-33(17-15-32)30-11-5-8-25-12-13-26(22-28(25)30)37-23-31(36)35-20-18-34(19-21-35)29-10-4-7-24-6-2-3-9-27(24)29/h2-13,22H,14-21,23H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.880 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE
Curated by ChEMBL
| Assay Description Receptor binding affinity for cloned human 5-hydroxytryptamine 1D receptor in Cos-7 cells |
J Med Chem 40: 3974-8 (1998)
Article DOI: 10.1021/jm9703552 BindingDB Entry DOI: 10.7270/Q2FT8K57 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1A
(Homo sapiens (Human)) | BDBM50454687
(CHEMBL2112661)Show SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)N3CCN(CC3)c3cccc4ccccc34)cc12 Show InChI InChI=1S/C31H34N4O2/c1-32-14-16-33(17-15-32)30-11-5-8-25-12-13-26(22-28(25)30)37-23-31(36)35-20-18-34(19-21-35)29-10-4-7-24-6-2-3-9-27(24)29/h2-13,22H,14-21,23H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 114 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE
Curated by ChEMBL
| Assay Description Receptor binding affinity for cloned human 5-hydroxytryptamine 1A receptor in HeLa cells |
J Med Chem 40: 3974-8 (1998)
Article DOI: 10.1021/jm9703552 BindingDB Entry DOI: 10.7270/Q2FT8K57 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 1B
(Homo sapiens (Human)) | BDBM50454687
(CHEMBL2112661)Show SMILES CN1CCN(CC1)c1cccc2ccc(OCC(=O)N3CCN(CC3)c3cccc4ccccc34)cc12 Show InChI InChI=1S/C31H34N4O2/c1-32-14-16-33(17-15-32)30-11-5-8-25-12-13-26(22-28(25)30)37-23-31(36)35-20-18-34(19-21-35)29-10-4-7-24-6-2-3-9-27(24)29/h2-13,22H,14-21,23H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Centre de Recherche Pierre FABRE
Curated by ChEMBL
| Assay Description Agonist activity at 5-hydroxytryptamine 1B receptor by measuring the inhibition of forskolin-stimulated cAMP formation |
J Med Chem 40: 3974-8 (1998)
Article DOI: 10.1021/jm9703552 BindingDB Entry DOI: 10.7270/Q2FT8K57 |
More data for this Ligand-Target Pair | |