Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity protein kinase CLK2
(Homo sapiens (Human)) | BDBM317455
(4-(4-(cyclopentyloxy)-5-(4- hydroxyphenyl)-7H-pyrr...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(c[nH]c3n2)-c2ccc(O)cc2)c(OC)c1 Show InChI InChI=1S/C26H27N5O4/c1-27-24(33)16-9-12-20(21(13-16)34-2)29-26-30-23-22(25(31-26)35-18-5-3-4-6-18)19(14-28-23)15-7-10-17(32)11-8-15/h7-14,18,32H,3-6H2,1-2H3,(H,27,33)(H2,28,29,30,31) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 53.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM317455
(4-(4-(cyclopentyloxy)-5-(4- hydroxyphenyl)-7H-pyrr...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(c[nH]c3n2)-c2ccc(O)cc2)c(OC)c1 Show InChI InChI=1S/C26H27N5O4/c1-27-24(33)16-9-12-20(21(13-16)34-2)29-26-30-23-22(25(31-26)35-18-5-3-4-6-18)19(14-28-23)15-7-10-17(32)11-8-15/h7-14,18,32H,3-6H2,1-2H3,(H,27,33)(H2,28,29,30,31) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |