Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity protein kinase TTK
(Homo sapiens (Human)) | BDBM317470
(3-chloro-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(Cl)c1 Show InChI InChI=1S/C27H25ClN6O4/c1-14-31-21-6-3-15(12-22(21)37-14)18-13-30-24-23(18)26(38-17-7-9-36-10-8-17)34-27(33-24)32-20-5-4-16(11-19(20)28)25(35)29-2/h3-6,11-13,17H,7-10H2,1-2H3,(H,29,35)(H2,30,32,33,34) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 4.12 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Homo sapiens (Human)) | BDBM317470
(3-chloro-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(Cl)c1 Show InChI InChI=1S/C27H25ClN6O4/c1-14-31-21-6-3-15(12-22(21)37-14)18-13-30-24-23(18)26(38-17-7-9-36-10-8-17)34-27(33-24)32-20-5-4-16(11-19(20)28)25(35)29-2/h3-6,11-13,17H,7-10H2,1-2H3,(H,29,35)(H2,30,32,33,34) | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 29.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM317470
(3-chloro-N-methyl-4-(5-(2- methylbenzo[d]oxazol-6-...)Show SMILES CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(c[nH]c3n2)-c2ccc3nc(C)oc3c2)c(Cl)c1 Show InChI InChI=1S/C27H25ClN6O4/c1-14-31-21-6-3-15(12-22(21)37-14)18-13-30-24-23(18)26(38-17-7-9-36-10-8-17)34-27(33-24)32-20-5-4-16(11-19(20)28)25(35)29-2/h3-6,11-13,17H,7-10H2,1-2H3,(H,29,35)(H2,30,32,33,34) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 226 | n/a | n/a | n/a | n/a | n/a | n/a |
Signal Pharmaceuticals, LLC
US Patent
| Assay Description The kinase activity is measured using a radioactivity based kinase assay, which measures the incorporation of a radioactively labeled phosphate moiet... |
US Patent US9623028 (2017)
BindingDB Entry DOI: 10.7270/Q2VQ34R8 |
More data for this Ligand-Target Pair | |