Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 396.4 BDBM50058249

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuromedin-K receptor (Homo sapiens (Human))	BDBM50058249 (CHEMBL53800 | Phenyl-[(3-phenyl-isoquinoline-1-car...) Show SMILES COC(=O)C(NC(=O)c1nc(cc2ccccc12)-c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H20N2O3/c1-30-25(29)22(18-12-6-3-7-13-18)27-24(28)23-20-15-9-8-14-19(20)16-21(26-23)17-10-4-2-5-11-17/h2-16,22H,1H3,(H,27,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Milano Curated by ChEMBL					Assay Description Inhibition of [125I]-MePhe7-Neurokinin B (NKB) binding in human Tachykinin receptor 3 of chinese hamster ovary (hNK-3-CHO) cell membranes.				J Med Chem 40: 1794-807 (1997) Article DOI: 10.1021/jm960818o BindingDB Entry DOI: 10.7270/Q24T6HHB
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