Found 6 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM445211
((Z)-Methyl 3-(((4-((2-(dimethylamino)ethyl)carbamo...)Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C29H30N4O4/c1-18-16-23-24(17-22(18)29(36)37-4)32-28(35)25(23)26(19-8-6-5-7-9-19)31-21-12-10-20(11-13-21)27(34)30-14-15-33(2)3/h5-13,16-17,31H,14-15H2,1-4H3,(H,30,34)(H,32,35)/b26-25- | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| 11.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED
US Patent
| Assay Description
The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the... |
US Patent US10669235 (2020)
BindingDB Entry DOI: 10.7270/Q2XW4NVJ |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 3
(Homo sapiens (Human)) | BDBM445211
((Z)-Methyl 3-(((4-((2-(dimethylamino)ethyl)carbamo...)Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C29H30N4O4/c1-18-16-23-24(17-22(18)29(36)37-4)32-28(35)25(23)26(19-8-6-5-7-9-19)31-21-12-10-20(11-13-21)27(34)30-14-15-33(2)3/h5-13,16-17,31H,14-15H2,1-4H3,(H,30,34)(H,32,35)/b26-25- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 14.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED
US Patent
| Assay Description
The inhibitory activities of compounds of the invention against FGFR3 (FGFR3 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR3 prote... |
US Patent US10669235 (2020)
BindingDB Entry DOI: 10.7270/Q2XW4NVJ |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human)) | BDBM445211
((Z)-Methyl 3-(((4-((2-(dimethylamino)ethyl)carbamo...)Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C29H30N4O4/c1-18-16-23-24(17-22(18)29(36)37-4)32-28(35)25(23)26(19-8-6-5-7-9-19)31-21-12-10-20(11-13-21)27(34)30-14-15-33(2)3/h5-13,16-17,31H,14-15H2,1-4H3,(H,30,34)(H,32,35)/b26-25- | PDB
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 18.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED
US Patent
| Assay Description
The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the... |
US Patent US10669235 (2020)
BindingDB Entry DOI: 10.7270/Q2XW4NVJ |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM445211
((Z)-Methyl 3-(((4-((2-(dimethylamino)ethyl)carbamo...)Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C29H30N4O4/c1-18-16-23-24(17-22(18)29(36)37-4)32-28(35)25(23)26(19-8-6-5-7-9-19)31-21-12-10-20(11-13-21)27(34)30-14-15-33(2)3/h5-13,16-17,31H,14-15H2,1-4H3,(H,30,34)(H,32,35)/b26-25- | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 28.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED
US Patent
| Assay Description
The inhibitory activities of compounds of the invention against VEGFR2 (VEGFR2 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR2 pr... |
US Patent US10669235 (2020)
BindingDB Entry DOI: 10.7270/Q2XW4NVJ |
More data for this
Ligand-Target Pair | |
Fibroblast growth factor receptor 1
(Homo sapiens (Human)) | BDBM445211
((Z)-Methyl 3-(((4-((2-(dimethylamino)ethyl)carbamo...)Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C29H30N4O4/c1-18-16-23-24(17-22(18)29(36)37-4)32-28(35)25(23)26(19-8-6-5-7-9-19)31-21-12-10-20(11-13-21)27(34)30-14-15-33(2)3/h5-13,16-17,31H,14-15H2,1-4H3,(H,30,34)(H,32,35)/b26-25- | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 44.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED
US Patent
| Assay Description
The inhibitory activities of compounds of the invention against FGFR1 (FGFR1 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR1 prote... |
US Patent US10669235 (2020)
BindingDB Entry DOI: 10.7270/Q2XW4NVJ |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 1
(Homo sapiens (Human)) | BDBM445211
((Z)-Methyl 3-(((4-((2-(dimethylamino)ethyl)carbamo...)Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C29H30N4O4/c1-18-16-23-24(17-22(18)29(36)37-4)32-28(35)25(23)26(19-8-6-5-7-9-19)31-21-12-10-20(11-13-21)27(34)30-14-15-33(2)3/h5-13,16-17,31H,14-15H2,1-4H3,(H,30,34)(H,32,35)/b26-25- | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| 123 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
RESPIVERT LIMITED
US Patent
| Assay Description
The inhibitory activities of compounds of the invention against VEGFR1 (VEGFR1 Kinase Enzyme System: Promega), were evaluated by mixing the VEGFR1 pr... |
US Patent US10669235 (2020)
BindingDB Entry DOI: 10.7270/Q2XW4NVJ |
More data for this
Ligand-Target Pair | |