Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 1' and Ligand = 'BDBM445211'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM445211 ((Z)-Methyl 3-(((4-((2-(dimethylamino)ethyl)carbamo...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C29H30N4O4/c1-18-16-23-24(17-22(18)29(36)37-4)32-28(35)25(23)26(19-8-6-5-7-9-19)31-21-12-10-20(11-13-21)27(34)30-14-15-33(2)3/h5-13,16-17,31H,14-15H2,1-4H3,(H,30,34)(H,32,35)/b26-25-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	44.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against FGFR1 (FGFR1 Kinase Enzyme System: Promega), were evaluated by mixing the FGFR1 prote...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
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