Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348972
(CHEMBL1808221)Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2C2CC(C)N=N2)c1 |c:22| Show InChI InChI=1S/C16H16N4O4/c1-9-6-12(20-19-9)13-14(21)17-8-18-15(13)24-11-5-3-4-10(7-11)16(22)23-2/h3-5,7-9,12H,6H2,1-2H3,(H,17,18,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50348972
(CHEMBL1808221)Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2C2CC(C)N=N2)c1 |c:22| Show InChI InChI=1S/C16H16N4O4/c1-9-6-12(20-19-9)13-14(21)17-8-18-15(13)24-11-5-3-4-10(7-11)16(22)23-2/h3-5,7-9,12H,6H2,1-2H3,(H,17,18,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant MET using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348972
(CHEMBL1808221)Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2C2CC(C)N=N2)c1 |c:22| Show InChI InChI=1S/C16H16N4O4/c1-9-6-12(20-19-9)13-14(21)17-8-18-15(13)24-11-5-3-4-10(7-11)16(22)23-2/h3-5,7-9,12H,6H2,1-2H3,(H,17,18,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |