Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Lysophosphatidic acid receptor 1
(Homo sapiens (Human)) | BDBM251671
(US10100018, Example 7 | US9464060, 7)Show SMILES COC1CC(CN(Cc2ccc(cc2)C(O)=O)C(=O)c2ccc(Oc3ccccc3F)cc2)C1 |(4.67,6.48,;3.33,5.71,;3.33,4.17,;4.42,3.08,;3.33,1.99,;3.33,.45,;2,-.32,;2,-1.86,;3.33,-2.63,;3.33,-4.17,;4.67,-4.94,;6,-4.17,;6,-2.63,;4.67,-1.86,;7.34,-4.94,;7.34,-6.48,;8.67,-4.17,;.67,.45,;.67,1.99,;-.67,-.32,;-.67,-1.86,;-2,-2.63,;-3.33,-1.86,;-4.67,-2.63,;-6,-1.86,;-6,-.32,;-7.34,.45,;-8.67,-.32,;-8.67,-1.86,;-7.34,-2.63,;-7.34,-4.17,;-3.33,-.32,;-2,.45,;2.25,3.08,)| Show InChI InChI=1S/C27H26FNO5/c1-33-23-14-19(15-23)17-29(16-18-6-8-21(9-7-18)27(31)32)26(30)20-10-12-22(13-11-20)34-25-5-3-2-4-24(25)28/h2-13,19,23H,14-17H2,1H3,(H,31,32) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | 25 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA1 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium i... |
US Patent US10100018 (2018)
BindingDB Entry DOI: 10.7270/Q2PR7Z0N |
More data for this Ligand-Target Pair | |
Lysophosphatidic acid receptor 5
(Homo sapiens (Human)) | BDBM251671
(US10100018, Example 7 | US9464060, 7)Show SMILES COC1CC(CN(Cc2ccc(cc2)C(O)=O)C(=O)c2ccc(Oc3ccccc3F)cc2)C1 |(4.67,6.48,;3.33,5.71,;3.33,4.17,;4.42,3.08,;3.33,1.99,;3.33,.45,;2,-.32,;2,-1.86,;3.33,-2.63,;3.33,-4.17,;4.67,-4.94,;6,-4.17,;6,-2.63,;4.67,-1.86,;7.34,-4.94,;7.34,-6.48,;8.67,-4.17,;.67,.45,;.67,1.99,;-.67,-.32,;-.67,-1.86,;-2,-2.63,;-3.33,-1.86,;-4.67,-2.63,;-6,-1.86,;-6,-.32,;-7.34,.45,;-8.67,-.32,;-8.67,-1.86,;-7.34,-2.63,;-7.34,-4.17,;-3.33,-.32,;-2,.45,;2.25,3.08,)| Show InChI InChI=1S/C27H26FNO5/c1-33-23-14-19(15-23)17-29(16-18-6-8-21(9-7-18)27(31)32)26(30)20-10-12-22(13-11-20)34-25-5-3-2-4-24(25)28/h2-13,19,23H,14-17H2,1H3,(H,31,32) | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | 37 |
Takeda Pharmaceutical Company Limited
US Patent
| Assay Description Engagement of the LPA5 receptor by its ligand, oleoyl-L-α-lysophosphatidic acid (LPA), leads to the release of intracellular stores of calcium into ... |
US Patent US9464060 (2016)
BindingDB Entry DOI: 10.7270/Q23R0RT0 |
More data for this Ligand-Target Pair | |