Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 464.4 BDBM372676

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM372676 (2-[4-(3,3-Difluoro-cyclobutoxy)-phenyl]-N-[2-(3,4-...) Show SMILES COc1cc(Cn2ncc(NC(=O)Cc3ccc(OC4CC(F)(F)C4)cc3)n2)cc(F)c1F Show InChI InChI=1S/C22H20F4N4O3/c1-32-18-7-14(6-17(23)21(18)24)12-30-27-11-19(29-30)28-20(31)8-13-2-4-15(5-3-13)33-16-9-22(25,26)10-16/h2-7,11,16H,8-10,12H2,1H3,(H,28,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
University of Alberta					Assay Description Stock solutions of test compounds are prepared to a concentration of 10 mM in DMSO. For the Cav3.2 assay, serial dilutions of the compounds are prepa...				J Med Chem 49: 1668-83 (2006) BindingDB Entry DOI: 10.7270/Q2794709
					More data for this Ligand-Target Pair