Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Programmed cell death 1 ligand/protein 1
(Homo sapiens-Homo sapiens (Human)) | BDBM50535765
(CHEMBL4578475)Show SMILES COc1cc(OCc2cccc(c2C)-c2cccc(COc3ccc(CN[C@H](CO)C(O)=O)c(OCc4cncc(c4)C#N)c3)c2C)ccc1CN[C@H](CO)C(O)=O |r| Show InChI InChI=1S/C44H46N4O10/c1-27-33(25-56-35-12-10-31(41(15-35)55-3)20-47-39(22-49)43(51)52)6-4-8-37(27)38-9-5-7-34(28(38)2)26-57-36-13-11-32(21-48-40(23-50)44(53)54)42(16-36)58-24-30-14-29(17-45)18-46-19-30/h4-16,18-19,39-40,47-50H,20-26H2,1-3H3,(H,51,52)(H,53,54)/t39-,40-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a |
Japan Tobacco Inc.
Curated by ChEMBL
| Assay Description
Inhibition of human PDL1 expressed in CHO-K1 cells co-expressing aAPC assessed as reduction in PDL1 interaction with human PD1 expressed in Jurkat T ... |
Bioorg Med Chem Lett 29: 2464-2467 (2019)
Article DOI: 10.1016/j.bmcl.2019.07.027
BindingDB Entry DOI: 10.7270/Q2M048ZK |
More data for this
Ligand-Target Pair | |
Programmed cell death 1 ligand 1
(Homo sapiens (Human)) | BDBM50535765
(CHEMBL4578475)Show SMILES COc1cc(OCc2cccc(c2C)-c2cccc(COc3ccc(CN[C@H](CO)C(O)=O)c(OCc4cncc(c4)C#N)c3)c2C)ccc1CN[C@H](CO)C(O)=O |r| Show InChI InChI=1S/C44H46N4O10/c1-27-33(25-56-35-12-10-31(41(15-35)55-3)20-47-39(22-49)43(51)52)6-4-8-37(27)38-9-5-7-34(28(38)2)26-57-36-13-11-32(21-48-40(23-50)44(53)54)42(16-36)58-24-30-14-29(17-45)18-46-19-30/h4-16,18-19,39-40,47-50H,20-26H2,1-3H3,(H,51,52)(H,53,54)/t39-,40-/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a |
Japan Tobacco Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to FC-tagged human PDL1 by SPR assay |
Bioorg Med Chem Lett 29: 2464-2467 (2019)
Article DOI: 10.1016/j.bmcl.2019.07.027
BindingDB Entry DOI: 10.7270/Q2M048ZK |
More data for this
Ligand-Target Pair | |