Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human)) | BDBM354742
(Preparation of N,N-dimethyl-5-(5-(3,4,5-trimethoxy...)Show SMILES COc1cc(cc(OC)c1OC)-c1cnc2[nH]cc(-c3ccc(nc3)N(C)C)c2c1 Show InChI InChI=1S/C23H24N4O3/c1-27(2)21-7-6-14(11-24-21)18-13-26-23-17(18)8-16(12-25-23)15-9-19(28-3)22(30-5)20(10-15)29-4/h6-13H,1-5H3,(H,25,26) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Rochester; Board of Regents of the University of Nebraska
US Patent
| Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ... |
US Patent US10485800 (2019)
BindingDB Entry DOI: 10.7270/Q22B91DW |
More data for this Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase 11
(Homo sapiens (Human)) | BDBM354742
(Preparation of N,N-dimethyl-5-(5-(3,4,5-trimethoxy...)Show SMILES COc1cc(cc(OC)c1OC)-c1cnc2[nH]cc(-c3ccc(nc3)N(C)C)c2c1 Show InChI InChI=1S/C23H24N4O3/c1-27(2)21-7-6-14(11-24-21)18-13-26-23-17(18)8-16(12-25-23)15-9-19(28-3)22(30-5)20(10-15)29-4/h6-13H,1-5H3,(H,25,26) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | <100 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Rochester
US Patent
| Assay Description 200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ... |
US Patent US9814704 (2017)
BindingDB Entry DOI: 10.7270/Q27H1MRN |
More data for this Ligand-Target Pair | |