Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Protein-tyrosine kinase 2-beta
(Homo sapiens (Human)) | BDBM245576
(US9428508, 31)Show SMILES COc1cc(ccc1Nc1nc2NCC(C)c2c(Nc2ccccc2N(C)S(C)(=O)=O)n1)N1CCOCC1 Show InChI InChI=1S/C26H33N7O4S/c1-17-16-27-24-23(17)25(28-19-7-5-6-8-21(19)32(2)38(4,34)35)31-26(30-24)29-20-10-9-18(15-22(20)36-3)33-11-13-37-14-12-33/h5-10,15,17H,11-14,16H2,1-4H3,(H3,27,28,29,30,31) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <20 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd.
US Patent
| Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... |
US Patent US9428508 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R3S |
More data for this
Ligand-Target Pair | |
Focal adhesion kinase 1
(Homo sapiens (Human)) | BDBM245576
(US9428508, 31)Show SMILES COc1cc(ccc1Nc1nc2NCC(C)c2c(Nc2ccccc2N(C)S(C)(=O)=O)n1)N1CCOCC1 Show InChI InChI=1S/C26H33N7O4S/c1-17-16-27-24-23(17)25(28-19-7-5-6-8-21(19)32(2)38(4,34)35)31-26(30-24)29-20-10-9-18(15-22(20)36-3)33-11-13-37-14-12-33/h5-10,15,17H,11-14,16H2,1-4H3,(H3,27,28,29,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | <30 | n/a | n/a | n/a | n/a | n/a | n/a |
Centaurus BioPharma Co., Ltd.
US Patent
| Assay Description
To measure inhibitory activity of FAK/PYK2 inhibitors, compounds were first prepare as a 1 mM stock in 100% DMSO and 3-fold serial dilution was perfo... |
US Patent US9428508 (2016)
BindingDB Entry DOI: 10.7270/Q2BR8R3S |
More data for this
Ligand-Target Pair | |