Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Casein kinase I isoform delta
(Homo sapiens (Human)) | BDBM255082
(US9475817, 39)Show SMILES COc1cc(nc(OC)n1)C(=O)Nc1cn2nc(ccc2n1)-c1cn(C)nc1-c1ccc(F)cc1 Show InChI InChI=1S/C23H19FN8O3/c1-31-11-15(21(30-31)13-4-6-14(24)7-5-13)16-8-9-19-26-18(12-32(19)29-16)27-22(33)17-10-20(34-2)28-23(25-17)35-3/h4-12H,1-3H3,(H,27,33) | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 10.2 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme, substrates (flu... |
US Patent US9475817 (2016)
BindingDB Entry DOI: 10.7270/Q2JQ0ZXH |
More data for this
Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM255082
(US9475817, 39)Show SMILES COc1cc(nc(OC)n1)C(=O)Nc1cn2nc(ccc2n1)-c1cn(C)nc1-c1ccc(F)cc1 Show InChI InChI=1S/C23H19FN8O3/c1-31-11-15(21(30-31)13-4-6-14(24)7-5-13)16-8-9-19-26-18(12-32(19)29-16)27-22(33)17-10-20(34-2)28-23(25-17)35-3/h4-12H,1-3H3,(H,27,33) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 75.7 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Bristol-Myers Squibb Company
US Patent
| Assay Description
The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 ul prepared from 15 ul additions of enzyme, substrates (flu... |
US Patent US9475817 (2016)
BindingDB Entry DOI: 10.7270/Q2JQ0ZXH |
More data for this
Ligand-Target Pair | |