Found 10 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Ras-related protein Rab-2A
(Canis lupus familiaris) | BDBM54585
(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[5-(4-m...)Show SMILES COc1ccc(cc1)-c1ccc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)s1 Show InChI InChI=1S/C26H30N2O2S/c1-19-4-5-20(2)24(18-19)27-14-16-28(17-15-27)26(29)13-11-23-10-12-25(31-23)21-6-8-22(30-3)9-7-21/h4-10,12,18H,11,13-17H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PCBioAssay
| 160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q21V5CCX |
More data for this Ligand-Target Pair | |
Cell division control protein 42 homolog
(Homo sapiens (Human)) | BDBM54585
(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[5-(4-m...)Show SMILES COc1ccc(cc1)-c1ccc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)s1 Show InChI InChI=1S/C26H30N2O2S/c1-19-4-5-20(2)24(18-19)27-14-16-28(17-15-27)26(29)13-11-23-10-12-25(31-23)21-6-8-22(30-3)9-7-21/h4-10,12,18H,11,13-17H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PCBioAssay
| 460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q20000HB |
More data for this Ligand-Target Pair | |
Ras-related C3 botulinum toxin substrate 1
(Mus musculus) | BDBM54585
(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[5-(4-m...)Show SMILES COc1ccc(cc1)-c1ccc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)s1 Show InChI InChI=1S/C26H30N2O2S/c1-19-4-5-20(2)24(18-19)27-14-16-28(17-15-27)26(29)13-11-23-10-12-25(31-23)21-6-8-22(30-3)9-7-21/h4-10,12,18H,11,13-17H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2PK0DK8 |
More data for this Ligand-Target Pair | |
Cell division control protein 42 homolog
(Homo sapiens (Human)) | BDBM54585
(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[5-(4-m...)Show SMILES COc1ccc(cc1)-c1ccc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)s1 Show InChI InChI=1S/C26H30N2O2S/c1-19-4-5-20(2)24(18-19)27-14-16-28(17-15-27)26(29)13-11-23-10-12-25(31-23)21-6-8-22(30-3)9-7-21/h4-10,12,18H,11,13-17H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 2.94E+3 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q23B5XM4 |
More data for this Ligand-Target Pair | |
Ras-related protein Rab-2A
(Canis lupus familiaris) | BDBM54585
(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[5-(4-m...)Show SMILES COc1ccc(cc1)-c1ccc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)s1 Show InChI InChI=1S/C26H30N2O2S/c1-19-4-5-20(2)24(18-19)27-14-16-28(17-15-27)26(29)13-11-23-10-12-25(31-23)21-6-8-22(30-3)9-7-21/h4-10,12,18H,11,13-17H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 2.48E+3 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q25H7DQC |
More data for this Ligand-Target Pair | |
Cell division control protein 42 homolog
(Homo sapiens (Human)) | BDBM54585
(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[5-(4-m...)Show SMILES COc1ccc(cc1)-c1ccc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)s1 Show InChI InChI=1S/C26H30N2O2S/c1-19-4-5-20(2)24(18-19)27-14-16-28(17-15-27)26(29)13-11-23-10-12-25(31-23)21-6-8-22(30-3)9-7-21/h4-10,12,18H,11,13-17H2,1-3H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2NK3CFW |
More data for this Ligand-Target Pair | |
GTPase KRas [1-37]
(Homo sapiens (Human)) | BDBM54585
(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[5-(4-m...)Show SMILES COc1ccc(cc1)-c1ccc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)s1 Show InChI InChI=1S/C26H30N2O2S/c1-19-4-5-20(2)24(18-19)27-14-16-28(17-15-27)26(29)13-11-23-10-12-25(31-23)21-6-8-22(30-3)9-7-21/h4-10,12,18H,11,13-17H2,1-3H3 | UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2C53J83 |
More data for this Ligand-Target Pair | |
GTPase KRas [1-37]
(Homo sapiens (Human)) | BDBM54585
(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[5-(4-m...)Show SMILES COc1ccc(cc1)-c1ccc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)s1 Show InChI InChI=1S/C26H30N2O2S/c1-19-4-5-20(2)24(18-19)27-14-16-28(17-15-27)26(29)13-11-23-10-12-25(31-23)21-6-8-22(30-3)9-7-21/h4-10,12,18H,11,13-17H2,1-3H3 | UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2JQ0ZF7 |
More data for this Ligand-Target Pair | |
Ras-related C3 botulinum toxin substrate 1
(Mus musculus) | BDBM54585
(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[5-(4-m...)Show SMILES COc1ccc(cc1)-c1ccc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)s1 Show InChI InChI=1S/C26H30N2O2S/c1-19-4-5-20(2)24(18-19)27-14-16-28(17-15-27)26(29)13-11-23-10-12-25(31-23)21-6-8-22(30-3)9-7-21/h4-10,12,18H,11,13-17H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2T43RHD |
More data for this Ligand-Target Pair | |
Ras-related protein Rab-7a
(Canis lupus familiaris) | BDBM54585
(1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[5-(4-m...)Show SMILES COc1ccc(cc1)-c1ccc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)s1 Show InChI InChI=1S/C26H30N2O2S/c1-19-4-5-20(2)24(18-19)27-14-16-28(17-15-27)26(29)13-11-23-10-12-25(31-23)21-6-8-22(30-3)9-7-21/h4-10,12,18H,11,13-17H2,1-3H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela... |
PubChem Bioassay (2009)
BindingDB Entry DOI: 10.7270/Q2F18X40 |
More data for this Ligand-Target Pair | |