Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
3-phosphoinositide-dependent protein kinase 1
(Homo sapiens (Human)) | BDBM50382801
(CHEMBL2023415)Show SMILES COc1ccc(cc1)-c1nc(Nc2cccc(NC(=O)NCCN3CCOCC3)c2)nc2nc[nH]c12 Show InChI InChI=1S/C25H28N8O3/c1-35-20-7-5-17(6-8-20)21-22-23(28-16-27-22)32-24(31-21)29-18-3-2-4-19(15-18)30-25(34)26-9-10-33-11-13-36-14-12-33/h2-8,15-16H,9-14H2,1H3,(H2,26,30,34)(H2,27,28,29,31,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 75 | n/a | n/a | n/a | n/a | n/a | n/a |
S*BIO Pte. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of PDK1 assessed as [gamma-33P]ATP incorporation into substrate after 1 hr by scintillation counting |
Bioorg Med Chem Lett 22: 2880-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.02.058
BindingDB Entry DOI: 10.7270/Q2668F6N |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50382801
(CHEMBL2023415)Show SMILES COc1ccc(cc1)-c1nc(Nc2cccc(NC(=O)NCCN3CCOCC3)c2)nc2nc[nH]c12 Show InChI InChI=1S/C25H28N8O3/c1-35-20-7-5-17(6-8-20)21-22-23(28-16-27-22)32-24(31-21)29-18-3-2-4-19(15-18)30-25(34)26-9-10-33-11-13-36-14-12-33/h2-8,15-16H,9-14H2,1H3,(H2,26,30,34)(H2,27,28,29,31,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
S*BIO Pte. Ltd
Curated by ChEMBL
| Assay Description
Inhibition of CDK2 using RbING as substrate after 2 hrs by luminescence assay |
Bioorg Med Chem Lett 22: 2880-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.02.058
BindingDB Entry DOI: 10.7270/Q2668F6N |
More data for this
Ligand-Target Pair | |