Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Acyl-CoA desaturase 1
(Mus musculus) | BDBM50296297
(3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluorome...)Show SMILES COc1ccc(cc1OCCO)C(=O)Nc1ccc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C22H20F3NO4S/c1-29-18-7-5-15(13-19(18)30-10-9-27)21(28)26-20-8-6-17(31-20)12-14-3-2-4-16(11-14)22(23,24)25/h2-8,11,13,27H,9-10,12H2,1H3,(H,26,28) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 76 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of stearoyl-CoA desaturase 1 in mouse microsome assessed as conversion of [14C]stearate to [14C]oleate |
Bioorg Med Chem Lett 19: 4159-66 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.123
BindingDB Entry DOI: 10.7270/Q2PZ58VW |
More data for this
Ligand-Target Pair | |
Stearoyl-CoA desaturase
(Homo sapiens (Human)) | BDBM50296297
(3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluorome...)Show SMILES COc1ccc(cc1OCCO)C(=O)Nc1ccc(Cc2cccc(c2)C(F)(F)F)s1 Show InChI InChI=1S/C22H20F3NO4S/c1-29-18-7-5-15(13-19(18)30-10-9-27)21(28)26-20-8-6-17(31-20)12-14-3-2-4-16(11-14)22(23,24)25/h2-8,11,13,27H,9-10,12H2,1H3,(H,26,28) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 145 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of stearoyl-CoA desaturase 1 in human microsome assessed as conversion of [14C]stearate to [14C]oleate |
Bioorg Med Chem Lett 19: 4159-66 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.123
BindingDB Entry DOI: 10.7270/Q2PZ58VW |
More data for this
Ligand-Target Pair | |