Found 8 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345285
(2-[[1-[(2-Isopropylphenyl)methyl]-5-(3- methoxyph...)Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1C(C)C Show InChI InChI=1S/C25H30N2O4/c1-17(2)22-12-7-6-9-19(22)15-27-23(18-10-8-11-21(13-18)30-5)14-20(26-27)16-31-25(3,4)24(28)29/h6-14,17H,15-16H2,1-5H3,(H,28,29) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2CR5ZGC |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345285
(2-[[1-[(2-Isopropylphenyl)methyl]-5-(3- methoxyph...)Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1C(C)C Show InChI InChI=1S/C25H30N2O4/c1-17(2)22-12-7-6-9-19(22)15-27-23(18-10-8-11-21(13-18)30-5)14-20(26-27)16-31-25(3,4)24(28)29/h6-14,17H,15-16H2,1-5H3,(H,28,29) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345285
(2-[[1-[(2-Isopropylphenyl)methyl]-5-(3- methoxyph...)Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1C(C)C Show InChI InChI=1S/C25H30N2O4/c1-17(2)22-12-7-6-9-19(22)15-27-23(18-10-8-11-21(13-18)30-5)14-20(26-27)16-31-25(3,4)24(28)29/h6-14,17H,15-16H2,1-5H3,(H,28,29) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345285
(2-[[1-[(2-Isopropylphenyl)methyl]-5-(3- methoxyph...)Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1C(C)C Show InChI InChI=1S/C25H30N2O4/c1-17(2)22-12-7-6-9-19(22)15-27-23(18-10-8-11-21(13-18)30-5)14-20(26-27)16-31-25(3,4)24(28)29/h6-14,17H,15-16H2,1-5H3,(H,28,29) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10202350 (2019)
BindingDB Entry DOI: 10.7270/Q20K2BPB |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 1
(Homo sapiens (Human)) | BDBM345285
(2-[[1-[(2-Isopropylphenyl)methyl]-5-(3- methoxyph...)Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1C(C)C Show InChI InChI=1S/C25H30N2O4/c1-17(2)22-12-7-6-9-19(22)15-27-23(18-10-8-11-21(13-18)30-5)14-20(26-27)16-31-25(3,4)24(28)29/h6-14,17H,15-16H2,1-5H3,(H,28,29) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 1
(Homo sapiens (Human)) | BDBM345285
(2-[[1-[(2-Isopropylphenyl)methyl]-5-(3- methoxyph...)Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1C(C)C Show InChI InChI=1S/C25H30N2O4/c1-17(2)22-12-7-6-9-19(22)15-27-23(18-10-8-11-21(13-18)30-5)14-20(26-27)16-31-25(3,4)24(28)29/h6-14,17H,15-16H2,1-5H3,(H,28,29) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2CR5ZGC |
More data for this Ligand-Target Pair | |
Malignant T-cell-amplified sequence 1
(Homo sapiens (human)) | BDBM345285
(2-[[1-[(2-Isopropylphenyl)methyl]-5-(3- methoxyph...)Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1C(C)C Show InChI InChI=1S/C25H30N2O4/c1-17(2)22-12-7-6-9-19(22)15-27-23(18-10-8-11-21(13-18)30-5)14-20(26-27)16-31-25(3,4)24(28)29/h6-14,17H,15-16H2,1-5H3,(H,28,29) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... |
US Patent US10202350 (2019)
BindingDB Entry DOI: 10.7270/Q20K2BPB |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 1
(Homo sapiens (Human)) | BDBM345285
(2-[[1-[(2-Isopropylphenyl)methyl]-5-(3- methoxyph...)Show SMILES COc1cccc(c1)-c1cc(COC(C)(C)C(O)=O)nn1Cc1ccccc1C(C)C Show InChI InChI=1S/C25H30N2O4/c1-17(2)22-12-7-6-9-19(22)15-27-23(18-10-8-11-21(13-18)30-5)14-20(26-27)16-31-25(3,4)24(28)29/h6-14,17H,15-16H2,1-5H3,(H,28,29) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 4.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this Ligand-Target Pair | |