Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 434.4 BDBM360517

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM360517 (N-((5-(3-methoxyphenyl)isoquinolin- 8-yl)methyl)-1...) Show SMILES COc1cccc(c1)-c1ccc(CNC(=O)c2ccn(n2)-c2ccccc2)c2cnccc12 Show InChI InChI=1S/C27H22N4O2/c1-33-22-9-5-6-19(16-22)23-11-10-20(25-18-28-14-12-24(23)25)17-29-27(32)26-13-15-31(30-26)21-7-3-2-4-8-21/h2-16,18H,17H2,1H3,(H,29,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharpe & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US9828369 (2017) BindingDB Entry DOI: 10.7270/Q2DN47C7
					More data for this Ligand-Target Pair