Found 5 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50140931
(CHEMBL3753782)Show InChI InChI=1S/C17H13N3O/c1-21-16-6-2-5-15-17(16)14(11-20-15)13(9-18)8-12-4-3-7-19-10-12/h2-8,10-11,20H,1H3/b13-8+ | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS
Curated by ChEMBL
| Assay Description Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam... |
Eur J Med Chem 124: 920-934 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.069 BindingDB Entry DOI: 10.7270/Q24X59S3 |
More data for this Ligand-Target Pair | |
Kinesin-like protein KIF20A
(Homo sapiens (Human)) | BDBM50140931
(CHEMBL3753782)Show InChI InChI=1S/C17H13N3O/c1-21-16-6-2-5-15-17(16)14(11-20-15)13(9-18)8-12-4-3-7-19-10-12/h2-8,10-11,20H,1H3/b13-8+ | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS
Curated by ChEMBL
| Assay Description Inhibition of microtubule-stimulated N-terminal MKLP-2 (56 to 505 residues) ATPase activity isolated from human hepatocellular carcinoma cells by pyr... |
Bioorg Med Chem 24: 721-34 (2016)
Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR |
More data for this Ligand-Target Pair | |
Kinesin-like protein KIF20A
(Homo sapiens (Human)) | BDBM50140931
(CHEMBL3753782)Show InChI InChI=1S/C17H13N3O/c1-21-16-6-2-5-15-17(16)14(11-20-15)13(9-18)8-12-4-3-7-19-10-12/h2-8,10-11,20H,1H3/b13-8+ | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS
Curated by ChEMBL
| Assay Description Inhibition of N-terminal MKLP2 (56 to 505 residues) ATPase basal activity isolated from human hepatocellular carcinoma cells by pyruvate kinase/lacta... |
Bioorg Med Chem 24: 721-34 (2016)
Article DOI: 10.1016/j.bmc.2015.12.042 BindingDB Entry DOI: 10.7270/Q29025NR |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50140931
(CHEMBL3753782)Show InChI InChI=1S/C17H13N3O/c1-21-16-6-2-5-15-17(16)14(11-20-15)13(9-18)8-12-4-3-7-19-10-12/h2-8,10-11,20H,1H3/b13-8+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS
Curated by ChEMBL
| Assay Description Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g... |
Eur J Med Chem 124: 920-934 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.069 BindingDB Entry DOI: 10.7270/Q24X59S3 |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50140931
(CHEMBL3753782)Show InChI InChI=1S/C17H13N3O/c1-21-16-6-2-5-15-17(16)14(11-20-15)13(9-18)8-12-4-3-7-19-10-12/h2-8,10-11,20H,1H3/b13-8+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CNRS
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK5/p25 using histone H1 as substrate after 30 mins in presence of [gamma-33 P] ATP by liquid scintillation counting... |
Eur J Med Chem 124: 920-934 (2016)
Article DOI: 10.1016/j.ejmech.2016.08.069 BindingDB Entry DOI: 10.7270/Q24X59S3 |
More data for this Ligand-Target Pair | |