Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 246.2 BDBM4736

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuraminidase (Influenza A virus (N9))	BDBM4736 (4,6-diamino-5-methanesulfonamidopyridine-2-carboxy...) Show SMILES CS(=O)(=O)Nc1c(N)cc(nc1N)C(O)=O Show InChI InChI=1S/C7H10N4O4S/c1-16(14,15)11-5-3(8)2-4(7(12)13)10-6(5)9/h2,11H,1H3,(H,12,13)(H4,8,9,10)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	6.5	37
BioCryst Pharmaceuticals, Inc.					Assay Description A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...				Bioorg Med Chem 13: 2665-78 (2005) Article DOI: 10.1016/j.bmc.2005.01.042 BindingDB Entry DOI: 10.7270/Q2SF2TD9
					More data for this Ligand-Target Pair