Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 410.2 BDBM50546055

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50546055 (CHEMBL4762280) Show SMILES Cc1c(Cl)nnc2sc(C(=O)NC3CN(C3)c3cnc(Cl)cn3)c(N)c12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of human M2 receptor/Gqi5 in presence of EC20 glutamate by calcium mobilization assay				Citation and Details Article DOI: 10.1016/j.bmcl.2019.05.026 BindingDB Entry DOI: 10.7270/Q2JM2F6M
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50546055 (CHEMBL4762280) Show SMILES Cc1c(Cl)nnc2sc(C(=O)NC3CN(C3)c3cnc(Cl)cn3)c(N)c12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	140	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of human M4 receptor/Gqi5 in presence of EC20 glutamate by calcium mobilization assay				Citation and Details Article DOI: 10.1016/j.bmcl.2019.05.026 BindingDB Entry DOI: 10.7270/Q2JM2F6M
					More data for this Ligand-Target Pair