Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 266.2 BDBM50022226

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thromboxane-A synthase (Homo sapiens (Human))	BDBM50022226 (6-Imidazol-1-ylmethyl-5-methyl-naphthalene-1-carbo...) Show SMILES Cc1c(Cn2ccnc2)ccc2c(cccc12)C(O)=O Show InChI InChI=1S/C16H14N2O2/c1-11-12(9-18-8-7-17-10-18)5-6-14-13(11)3-2-4-15(14)16(19)20/h2-8,10H,9H2,1H3,(H,19,20)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of thromboxane TXA2 synthetase from human platelets				J Med Chem 29: 1643-50 (1986) BindingDB Entry DOI: 10.7270/Q2C8289W
					More data for this Ligand-Target Pair
Cytochrome P450 11B1, mitochondrial (Rattus norvegicus)	BDBM50022226 (6-Imidazol-1-ylmethyl-5-methyl-naphthalene-1-carbo...) Show SMILES Cc1c(Cn2ccnc2)ccc2c(cccc12)C(O)=O Show InChI InChI=1S/C16H14N2O2/c1-11-12(9-18-8-7-17-10-18)5-6-14-13(11)3-2-4-15(14)16(19)20/h2-8,10H,9H2,1H3,(H,19,20)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of rat adrenal 11-beta-hydroxylase				J Med Chem 29: 1643-50 (1986) BindingDB Entry DOI: 10.7270/Q2C8289W
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (RAT)	BDBM50022226 (6-Imidazol-1-ylmethyl-5-methyl-naphthalene-1-carbo...) Show SMILES Cc1c(Cn2ccnc2)ccc2c(cccc12)C(O)=O Show InChI InChI=1S/C16H14N2O2/c1-11-12(9-18-8-7-17-10-18)5-6-14-13(11)3-2-4-15(14)16(19)20/h2-8,10H,9H2,1H3,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of cyclooxygenase from RBL-1 cells.				J Med Chem 29: 1643-50 (1986) BindingDB Entry DOI: 10.7270/Q2C8289W
					More data for this Ligand-Target Pair